Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Respiratory failure
ADR ID BADD_A03813
ADR Hierarchy
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.04      Respiratory acidoses
14.01.04.003      Respiratory failure
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.06      Respiratory failures (excl neonatal)
22.02.06.002      Respiratory failure
Description A disorder characterized by impaired gas exchange by the respiratory system resulting in hypoxia and a decrease in oxygenation of the tissues that may be associated with an increase in arterial levels of carbon dioxide. [CTCAE] Failure to adequately provide oxygen to cells of the body and to remove excess carbon dioxide from them. (Stedman, 25th ed) [MeSH]
MedDRA Code 10038695
MeSH ID D012131
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Failure respiratory | Other pulmonary insufficiency, not elsewhere classified | Pulmonary insufficiency following trauma and surgery | Respiration failure | Respiratory failure | Respiratory failure (excl neonatal) | Respiratory insufficiency | Ventilatory failure | Pulmonary failure | Hypercapnic respiratory failure | Restrictive respiratory insufficiency | Respiratory failure aggravated | Hypoxic respiratory failure | End stage lung disease | Respiratory failure type 1 | Respiratory failure type 2 | Hypoxemic respiratory failure | Hypoxaemic respiratory failure | Respiratory Insufficiency | Respiratory Failure | Respiratory Depression | Ventilatory Depression | Depressions, Ventilatory
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01962Roflumilast0.003662%
BADD_D01966Ropinirole--
BADD_D01968Ropivacaine hydrochloride--
BADD_D01970Rosiglitazone maleate--
BADD_D01978Ruxolitinib0.001784%
BADD_D01981Salmeterol0.003263%
BADD_D01987Sapropterin--
BADD_D01988Sapropterin dihydrochloride--
BADD_D01997Secobarbital--
BADD_D02006Selexipag0.000411%
BADD_D02011Sertraline hydrochloride--
BADD_D02015Sevoflurane0.000750%
BADD_D02018Sildenafil0.001450%
BADD_D02028Sirolimus0.001541%
BADD_D02029Sitagliptin0.000239%
BADD_D02031Sitaxentan--
BADD_D02032Sodium acetate--
BADD_D02034Sodium bicarbonate0.000427%
BADD_D02060Sotalol0.000422%
BADD_D02068Stavudine--
BADD_D02079Succinylcholine--
BADD_D02082Sufentanil0.000268%
BADD_D02084Sugammadex0.001239%
BADD_D02100Sunitinib--
BADD_D02105Tacrolimus0.012179%
BADD_D02106Tadalafil0.001952%
BADD_D02113Tamsulosin0.000076%
BADD_D02150Temozolomide--
BADD_D02167Terlipressin--
BADD_D02175Tetrabenazine0.001077%
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