Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Restlessness
ADR ID BADD_A03825
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.021      Restlessness
19      Psychiatric disorders
19.11      Changes in physical activity
19.11.02      Increased physical activity levels
19.11.02.002      Restlessness
Description A disorder characterized by an inability to rest, relax or be still. [CTCAE] A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions. [MeSH]
MedDRA Code 10038743
MeSH ID D011595
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Marked restlessness | Muscular unrest | Physically restless | Restless | Restlessness | Restlessness (drug related) | Restlessness (phenothiazine) | Restlessness marked | Unrest | Restlessness aggravated | Inner restlessness | Psychomotor Agitation | Psychomotor Hyperactivity | Hyperactivity, Psychomotor | Psychomotor Restlessness | Restlessness, Psychomotor | Agitation, Psychomotor | Excitement, Psychomotor | Psychomotor Excitement | Akathisia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00448Chlorthalidone--
BADD_D00471Ciprofloxacin--
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00475Citalopram0.000108%
BADD_D00477Citric acid0.360701%
BADD_D00480Clarithromycin0.000893%
BADD_D00481Clemastine fumarate--
BADD_D00499Clomipramine--
BADD_D00501Clonazepam0.000181%
BADD_D00502Clonidine--
BADD_D00503Clonidine hydrochloride--
BADD_D00511Clozapine--
BADD_D00515Cocaine hydrochloride--
BADD_D00545Cyclobenzaprine--
BADD_D00547Cyclopentolate0.001632%
BADD_D00548Cyclopentolate hydrochloride--
BADD_D00552Cyproheptadine--
BADD_D00553Cyproheptadine hydrochloride--
BADD_D00604Delavirdine mesylate--
BADD_D00612Desipramine--
BADD_D00613Desipramine hydrochloride--
BADD_D00615Desloratadine--
BADD_D00616Desmopressin0.001882%
BADD_D00621Desvenlafaxine0.001444%
BADD_D00627Dexchlorpheniramine maleate--
BADD_D00636Dextroamphetamine--
BADD_D00637Dextroamphetamine sulfate--
BADD_D00648Diazepam0.000448%
BADD_D00652Dichlorphenamide0.000646%
BADD_D00653Diclofenac0.000177%
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