Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Rhabdomyolysis
ADR ID BADD_A03877
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.05      Myopathies
15.05.05.002      Rhabdomyolysis
Description A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream. [CTCAE] Necrosis or disintegration of skeletal muscle often followed by myoglobinuria. [MeSH]
MedDRA Code 10039020
MeSH ID D012206
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Muscle dissolution | Rhabdomyolysis | Rhabdomyolyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00511Clozapine--
BADD_D00512Cobicistat--
BADD_D00513Cobimetinib0.000112%
BADD_D00514Cocaine0.000099%
BADD_D00518Colchicine0.000244%
BADD_D00545Cyclobenzaprine0.000096%
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine0.001105%
BADD_D00561Cytarabine hydrochloride--
BADD_D00566Dabrafenib0.000168%
BADD_D00578Dapagliflozin0.000768%
BADD_D00581Daptomycin0.002892%
BADD_D00586Darunavir--
BADD_D00587Darunavir ethanolate--
BADD_D00589Dasatinib--
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00611Desflurane--
BADD_D00629Dexmedetomidine0.000196%
BADD_D00636Dextroamphetamine0.000675%
BADD_D00637Dextroamphetamine sulfate--
BADD_D00648Diazepam0.000856%
BADD_D00653Diclofenac0.000243%
BADD_D00661Didanosine--
BADD_D00674Diltiazem0.000184%
BADD_D00686Diphenhydramine0.002082%
BADD_D00704Dolutegravir sodium0.000423%
BADD_D00706Donepezil0.000895%
BADD_D00725Doxycycline0.000022%
BADD_D00735Duloxetine hydrochloride--
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ADReCS-Target
ADR Term Drug Name Target