Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Sarcoma
ADR ID BADD_A03920
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.09      Musculoskeletal and connective tissue neoplasms
15.09.03      Malignant musculoskeletal and connective tissue neoplasms
15.09.03.002      Sarcoma
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.33      Soft tissue neoplasms malignant and unspecified
16.33.01      Soft tissue sarcomas histology unspecified
16.33.01.002      Sarcoma
Description A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant. [MeSH]
MedDRA Code 10039491
MeSH ID D012509
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Sarcoma | Sarcoma NOS | Sarcomas | Sarcoma, Soft Tissue | Sarcomas, Soft Tissue | Soft Tissue Sarcoma | Soft Tissue Sarcomas | Sarcoma, Epithelioid | Epithelioid Sarcoma | Epithelioid Sarcomas | Sarcomas, Epithelioid | Sarcoma, Spindle Cell | Sarcomas, Spindle Cell | Spindle Cell Sarcoma | Spindle Cell Sarcomas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00047Afatinib0.000168%
BADD_D00194Azacitidine0.000112%
BADD_D00195Azathioprine--
BADD_D00463Cidofovir--
BADD_D00464Cidofovir dihydrate--
BADD_D00511Clozapine0.001834%
BADD_D00535Crizotinib0.000112%
BADD_D00549Cyclophosphamide--
BADD_D00723Doxorubicin0.000616%
BADD_D00730Dronedarone0.000490%
BADD_D00854Etoposide0.000112%
BADD_D00964Foscarnet sodium--
BADD_D01133Ifosfamide--
BADD_D01253Lenalidomide0.000723%
BADD_D01281Levonorgestrel0.000709%
BADD_D01372Megestrol acetate--
BADD_D01418Methotrexate0.000114%
BADD_D01687Pazopanib0.000560%
BADD_D01913Ranitidine0.000025%
BADD_D02028Sirolimus0.000134%
BADD_D02058Sorafenib0.000168%
BADD_D02112Tamoxifen citrate--
BADD_D02150Temozolomide0.000112%
BADD_D02192Thalidomide--
BADD_D02312Ulipristal--
BADD_D02464Fingolimod0.000603%
BADD_D02470Nintedanib0.000112%
BADD_D02493Selinexor0.001332%
BADD_D02526Larotrectinib0.000168%
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ADReCS-Target
ADR Term Drug Name Target