Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Splenomegaly
ADR ID BADD_A04138
ADR Hierarchy
01      Blood and lymphatic system disorders
01.09      Spleen, lymphatic and reticuloendothelial system disorders
01.09.02      Spleen disorders
01.09.02.001      Splenomegaly
Description Enlargement of the spleen. [MeSH]
MedDRA Code 10041660
MeSH ID D013163
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Chronic congestive splenomegaly | Spleen dullness enlarged | Spleen enlarged | Splenomegaly | Megalosplenia | Hypersplenotrophy | Enlarged Spleen | Spleen, Enlarged
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01257Letrozole0.000263%
BADD_D01265Levetiracetam0.000278%
BADD_D01275Levofloxacin0.000042%
BADD_D01322Losartan0.000022%
BADD_D01392Mercaptopurine0.001041%
BADD_D01431Methylphenidate0.000041%
BADD_D01433Methylprednisolone0.000032%
BADD_D01465Miglustat0.012937%
BADD_D01470Minocycline0.000413%
BADD_D01506Muromonab-cd3--
BADD_D01533Naproxen--
BADD_D01567Nilotinib0.002675%
BADD_D01592Obeticholic acid0.003649%
BADD_D01633Oxaliplatin0.001780%
BADD_D01637Oxcarbazepine--
BADD_D01653Paclitaxel--
BADD_D01693Pegfilgrastim--
BADD_D01717Pentamidine--
BADD_D01718Pentamidine isethionate--
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01765Phenytoin0.000191%
BADD_D01789Plerixafor octahydrochloride--
BADD_D01799Ponatinib0.000168%
BADD_D01804Posaconazole--
BADD_D01826Praziquantel0.001691%
BADD_D01831Prednisolone0.000087%
BADD_D01834Prednisone0.000040%
BADD_D01835Pregabalin--
BADD_D01858Propagermanium--
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