Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Tendon disorder
ADR ID BADD_A04246
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.07      Tendon, ligament and cartilage disorders
15.07.01      Tendon disorders
15.07.01.002      Tendon disorder
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.07      Muscle, tendon and ligament injuries
12.01.07.019      Tendon disorder
Description Clinical syndrome describing overuse tendon injuries characterized by a combination of PAIN, diffuse or localized swelling, and impaired performance. | A disorder of TENDONS characterized by COLLAGEN degeneration, other changes to tenocytes and the EXTRACELLULAR MATRIX, and a lack of inflammatory cells. It is caused by aging, MICROTRAUMA, or vascular compromise. Tendinosis is not a clinical diagnosis and can be confirmed only by histopathological findings. | Inflammation of TENDONS. It is characterized by the degeneration of tendons accompanied by an inflammatory repair response, fibroblastic proliferation, and formation of granulation tissue. Tendinitis is not a clinical diagnosis and can be confirmed only by histopathological findings. [MeSH]
MedDRA Code 10043239
MeSH ID D052256
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Disorder tendon | Disorders of bursae and tendons in shoulder region, unspecified | Tenden disorder | Tendon disorder | Tendon disorder NOS | Achilles tendon thickening | Tendon friction rub | Tendinosis | Tendon thickening | Tendinopathy | Tendinopathies | Tendonopathy | Tendonopathies | Tendinoses | Tendonosis | Tendonoses | Tendinitis | Tendinitides | Tendonitis | Tendonitides
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01501Moxifloxacin--
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01533Naproxen--
BADD_D01557Nevirapine0.010608%
BADD_D01598Ofloxacin0.000250%
BADD_D01611Omega-3-acid ethyl esters--
BADD_D01771Pilocarpine hydrochloride--
BADD_D01831Prednisolone0.000070%
BADD_D01834Prednisone0.000033%
BADD_D01835Pregabalin0.000166%
BADD_D01898Rabeprazole--
BADD_D01903Raloxifene--
BADD_D01904Raloxifene hydrochloride--
BADD_D01909Ramipril0.000140%
BADD_D01950Risedronic acid--
BADD_D01956Rivastigmine tartrate--
BADD_D01971Rosuvastatin0.000089%
BADD_D02026Simvastatin0.000052%
BADD_D02047Sodium oxybate0.000268%
BADD_D02105Tacrolimus--
BADD_D02236Tofacitinib0.003472%
BADD_D02254Tramadol--
BADD_D02329Valproic acid0.000100%
BADD_D02369Voriconazole0.005809%
BADD_D02407Upadacitinib0.000530%
BADD_D02412Octreotide--
BADD_D02436Atorvastatin--
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