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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
Drug Name
Drug ID
ATC Code
DrugBank ID
KEGG ID
PubChem ID
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ADR Ontology
ADR Term
Therapeutic response decreased
ADR ID
BADD_A04266
ADR Hierarchy
08
General disorders and administration site conditions
08.06
Therapeutic and nontherapeutic effects (excl toxicity)
08.06.01
Therapeutic and nontherapeutic responses
08.06.01.016
Therapeutic response decreased
Description
Not Available
MedDRA Code
10043414
MeSH ID
Not Available
ADR Severity Grade (FAERS)
Not Available
ADR Severity Grade (CTCAE)
Not Available
Synonym
Not as effective | Therapeutic response decreased | Subtherapeutic response | Reduced therapeutic response with drug substitution
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D01086
Hydrocortisone
-
-
BADD_D01087
Hydrocortisone acetate
-
-
BADD_D01096
Hydromorphone
0.001240%
BADD_D01103
Hydroxychloroquine
0.001859%
BADD_D01110
Hydroxyurea
0.000280%
BADD_D01111
Hydroxyzine
-
-
BADD_D01126
Icosapent ethyl
-
BADD_D01136
Imatinib
0.007074%
BADD_D01147
Indacaterol
-
-
BADD_D01156
Indomethacin
-
-
BADD_D01191
Ipratropium
-
-
BADD_D01194
Irbesartan
0.000404%
BADD_D01230
Ketoconazole
0.000145%
BADD_D01240
Lactulose
-
-
BADD_D01245
Lansoprazole
-
-
BADD_D01252
Leflunomide
0.002871%
BADD_D01257
Letrozole
-
-
BADD_D01260
Leuprolide acetate
0.011616%
BADD_D01272
Levocetirizine
0.000661%
BADD_D01275
Levofloxacin
0.000219%
BADD_D01285
Levothyroxine
0.000035%
BADD_D01287
Lidocaine
-
-
BADD_D01292
Linagliptin
0.000825%
BADD_D01300
Lisinopril
-
-
BADD_D01303
Lithium carbonate
-
-
BADD_D01304
Lithium cation
0.000518%
BADD_D01317
Loratadine
-
-
BADD_D01318
Lorazepam
-
-
BADD_D01326
Loxapine
-
-
BADD_D01359
Mechlorethamine
0.000627%
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