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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
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KEGG ID
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ADR Ontology
ADR Term
Therapeutic response decreased
ADR ID
BADD_A04266
ADR Hierarchy
08
General disorders and administration site conditions
08.06
Therapeutic and nontherapeutic effects (excl toxicity)
08.06.01
Therapeutic and nontherapeutic responses
08.06.01.016
Therapeutic response decreased
Description
Not Available
MedDRA Code
10043414
MeSH ID
Not Available
ADR Severity Grade (FAERS)
Not Available
ADR Severity Grade (CTCAE)
Not Available
Synonym
Not as effective | Therapeutic response decreased | Subtherapeutic response | Reduced therapeutic response with drug substitution
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D01397
Mesalamine
0.000494%
BADD_D01425
Methyldopa
-
-
BADD_D01431
Methylphenidate
0.000502%
BADD_D01445
Metoprolol
0.000043%
BADD_D01459
Midazolam
-
-
BADD_D01473
Minoxidil
0.001052%
BADD_D01477
Misoprostol
-
-
BADD_D01484
Modafinil
0.001399%
BADD_D01491
Mometasone furoate
-
-
BADD_D01496
Montelukast
0.000089%
BADD_D01507
Mycophenolate mofetil
-
-
BADD_D01564
Nicotine
0.001379%
BADD_D01566
Nifedipine
-
-
BADD_D01567
Nilotinib
0.002653%
BADD_D01579
Nitroglycerin
-
-
BADD_D01582
Nizatidine
-
-
BADD_D01599
Olanzapine
0.002042%
BADD_D01614
Omeprazole
-
-
BADD_D01642
Oxtriphylline
-
-
BADD_D01643
Oxybutynin
0.000288%
BADD_D01656
Paliperidone
0.859849%
BADD_D01662
Pamidronic acid
0.000126%
BADD_D01668
Pantoprazole
-
-
BADD_D01679
Paroxetine
0.000043%
BADD_D01684
Pasireotide
0.000596%
BADD_D01708
Penciclovir
-
-
BADD_D01752
Phenobarbital
-
-
BADD_D01765
Phenytoin
-
-
BADD_D01771
Pilocarpine hydrochloride
0.012628%
BADD_D01788
Plerixafor
0.005747%
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