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ADR Term
ADReCS ID
MedDRA Code
MeSH ID
Drug Name
Drug ID
ATC Code
DrugBank ID
KEGG ID
PubChem ID
CAS RN
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ADR Ontology
ADR Term
Therapeutic response decreased
ADR ID
BADD_A04266
ADR Hierarchy
08
General disorders and administration site conditions
08.06
Therapeutic and nontherapeutic effects (excl toxicity)
08.06.01
Therapeutic and nontherapeutic responses
08.06.01.016
Therapeutic response decreased
Description
Not Available
MedDRA Code
10043414
MeSH ID
Not Available
ADR Severity Grade (FAERS)
Not Available
ADR Severity Grade (CTCAE)
Not Available
Synonym
Not as effective | Therapeutic response decreased | Subtherapeutic response | Reduced therapeutic response with drug substitution
Drugs Leading to the ADR
Drug ID
Drug Name
ADR Frequency (FAERS)
ADR Severity Grade (FAERS)
BADD_D01799
Ponatinib
0.000414%
BADD_D01804
Posaconazole
0.018440%
BADD_D01814
Pralatrexate
0.000112%
BADD_D01824
Pravastatin
-
-
BADD_D01831
Prednisolone
0.000262%
BADD_D01834
Prednisone
0.000201%
BADD_D01840
Primidone
-
-
BADD_D01852
Progesterone
-
-
BADD_D01864
Propofol
0.006645%
BADD_D01913
Ranitidine
-
-
BADD_D01933
Ribavirin
0.080303%
BADD_D01936
Rifampicin
0.001867%
BADD_D01951
Risperidone
0.003176%
BADD_D01957
Rizatriptan
0.000532%
BADD_D01966
Ropinirole
-
-
BADD_D01978
Ruxolitinib
-
-
BADD_D02026
Simvastatin
-
-
BADD_D02028
Sirolimus
0.000362%
BADD_D02029
Sitagliptin
0.000297%
BADD_D02047
Sodium oxybate
0.010461%
BADD_D02060
Sotalol
-
-
BADD_D02079
Succinylcholine
-
-
BADD_D02082
Sufentanil
0.000179%
BADD_D02093
Sulfasalazine
0.000909%
BADD_D02098
Sumatriptan
0.000189%
BADD_D02103
Suvorexant
0.001111%
BADD_D02105
Tacrolimus
0.001931%
BADD_D02106
Tadalafil
-
-
BADD_D02113
Tamsulosin
-
-
BADD_D02115
Tapentadol
0.004651%
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