Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Type I hypersensitivity
ADR ID BADD_A04407
ADR Hierarchy
10      Immune system disorders
10.01      Allergic conditions
10.01.03      Allergic conditions NEC
10.01.03.006      Type I hypersensitivity
Description Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability. [MeSH]
MedDRA Code 10045240
MeSH ID D006969
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypersensitivity type I | Hypersensitivity type I NOS | Immediate hypersensitivity | Immediate hypersensitivity reaction | Type I hypersensitivity | Hypersensitivity, Immediate | Hypersensitivities, Immediate | Immediate Hypersensitivities | Immediate Hypersensitivity | IgE-Mediated Hypersensitivity | Hypersensitivities, IgE-Mediated | Hypersensitivity, IgE-Mediated | IgE Mediated Hypersensitivity | IgE-Mediated Hypersensitivities | Hypersensitivity, Type I | Hypersensitivities, Type I | Type I Hypersensitivities | Atopic Hypersensitivity | Atopic Hypersensitivities | Hypersensitivities, Atopic | Hypersensitivity, Atopic | Type I Hypersensitivity
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01178Iodixanol0.007113%
BADD_D01180Iohexol0.007113%
BADD_D01182Iopromide0.046237%
BADD_D01186Ioversol0.029876%
BADD_D01191Ipratropium--
BADD_D01231Ketoprofen0.004481%
BADD_D01245Lansoprazole0.000348%
BADD_D01257Letrozole0.000263%
BADD_D01260Leuprolide acetate0.002151%
BADD_D01262Levalbuterol--
BADD_D01275Levofloxacin0.003268%
BADD_D01285Levothyroxine0.000017%
BADD_D01322Losartan0.000025%
BADD_D01375Meloxicam sodium--
BADD_D01433Methylprednisolone0.000096%
BADD_D01449Metronidazole0.000263%
BADD_D01490Mometasone0.000131%
BADD_D01491Mometasone furoate--
BADD_D01498Morphine0.000223%
BADD_D01598Ofloxacin0.000167%
BADD_D01601Olaparib0.000112%
BADD_D01617Ondansetron--
BADD_D01623Oritavancin0.000049%
BADD_D01633Oxaliplatin0.003246%
BADD_D01653Paclitaxel0.001511%
BADD_D01668Pantoprazole0.000229%
BADD_D01864Propofol0.000268%
BADD_D01898Rabeprazole0.000260%
BADD_D01936Rifampicin0.002800%
BADD_D01959Rocuronium0.000142%
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