Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Quadriparesis
ADR ID BADD_A04854
ADR Hierarchy
17      Nervous system disorders
17.01      Movement disorders (incl parkinsonism)
17.01.04      Paralysis and paresis (excl cranial nerve)
17.01.04.012      Quadriparesis
Description Severe or complete loss of motor function in all four limbs which may result from BRAIN DISEASES; SPINAL CORD DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or rarely MUSCULAR DISEASES. The locked-in syndrome is characterized by quadriplegia in combination with cranial muscle paralysis. Consciousness is spared and the only retained voluntary motor activity may be limited eye movements. This condition is usually caused by a lesion in the upper BRAIN STEM which injures the descending cortico-spinal and cortico-bulbar tracts. [MeSH]
MedDRA Code 10049680
MeSH ID D011782
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Quadriparesis | Spastic quadriparesis | Tetraparesis | Quadriplegia | Quadriplegias | Tetraplegia | Tetraplegias | Spastic Quadriplegia | Quadriplegia, Spastic | Quadriplegias, Spastic | Spastic Quadriplegias | Spastic Tetraplegia | Spastic Tetraplegias | Tetraplegia, Spastic | Tetraplegias, Spastic | Paralysis, Spinal, Quadriplegic | Quadripareses | Flaccid Quadriplegia | Flaccid Quadriplegias | Quadriplegia, Flaccid | Quadriplegias, Flaccid | Flaccid Tetraplegia | Flaccid Tetraplegias | Tetraplegia, Flaccid | Tetraplegias, Flaccid | Locked-In Syndrome | Locked In Syndrome | Locked-In Syndromes | Syndrome, Locked-In | Syndromes, Locked-In
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00130Amphetamine0.000080%
BADD_D00178Atenolol0.000039%
BADD_D00209Baclofen0.000174%
BADD_D00349Capecitabine0.000168%
BADD_D00479Cladribine--
BADD_D00504Clopidogrel0.000203%
BADD_D00563Dabigatran0.000245%
BADD_D00623Dexamethasone0.000145%
BADD_D00648Diazepam0.000050%
BADD_D00932Fluoxetine0.000049%
BADD_D00979Furosemide0.000014%
BADD_D01275Levofloxacin0.000063%
BADD_D01401Metformin0.000016%
BADD_D01405Methadone0.000265%
BADD_D01418Methotrexate0.000114%
BADD_D01433Methylprednisolone0.000048%
BADD_D01465Miglustat0.004312%
BADD_D01506Muromonab-cd3--
BADD_D01567Nilotinib0.000112%
BADD_D01580Nitrous oxide0.000179%
BADD_D01599Olanzapine0.000210%
BADD_D01831Prednisolone0.000052%
BADD_D01835Pregabalin0.000052%
BADD_D01858Propagermanium--
BADD_D01888Quetiapine0.000136%
BADD_D01951Risperidone0.000121%
BADD_D01954Rivaroxaban0.000222%
BADD_D02026Simvastatin0.000033%
BADD_D02105Tacrolimus0.000297%
BADD_D02150Temozolomide0.000112%
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