Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Nitrous oxide
Drug ID BADD_D01580
Description Nitrous oxide, commonly known as "laughing gas", is a chemical compound with the chemical formula N2O. At room temperature, it is a colorless non-flammable gas, with a pleasant, slightly sweet odor and taste. It is used in surgery and dentistry for its anesthetic and analgesic effects. It is known as "laughing gas" due to the euphoric effects of inhaling it, a property that has led to its recreational use as an inhalant drug.
Indications and Usage Not Available
Marketing Status approved; vet_approved
ATC Code N01AX13
DrugBank ID DB06690
KEGG ID D00102
MeSH ID D009609
PubChem ID 948
TTD Drug ID D0O8DI
NDC Product Code 12121-002; 21220-122; 42602-003; 51486-007; 55037-301; 55404-002; 72343-001; 10736-017; 33335-003; 44076-012; 46123-007; 12213-593; 18482-002; 20703-003; 34057-010; 10014-003; 46123-006; 53440-003; 63978-201; 24312-003; 48273-002; 49575-003; 54218-800; 62273-005; 67477-002; 17575-011; 43621-003; 55050-0018; 70151-004; 44517-020; 50554-005; 62097-0004; 67525-400; 10167-200; 11054-007; 46362-003; 52086-015; 62045-8333; 72276-002; 10252-003; 52568-002; 53511-003; 54260-001; 59579-004
UNII K50XQU1029
Synonyms Nitrous Oxide | Oxide, Nitrous | Laughing Gas | Gas, Laughing | Nitrogen Protoxide
Chemical Information
Molecular Formula N2O
CAS Registry Number 10024-97-2
SMILES [N-]=[N+]=O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Acute myocardial infarction24.04.04.001; 02.02.02.0010.000268%Not Available
Aggression19.05.01.0010.000482%Not Available
Agitation19.06.02.001; 17.02.05.0120.000482%
Amnesia19.20.01.001; 17.03.02.0010.000393%
Anaemia macrocytic14.12.01.002; 01.03.02.0020.000268%Not Available
Anaemia megaloblastic14.12.01.003; 01.03.02.003--Not Available
Aphasia19.21.01.001; 17.02.03.0010.000179%
Arrhythmia02.03.02.001--Not Available
Asphyxia22.02.02.001; 12.01.08.0110.000804%Not Available
Aspiration22.02.07.0070.000179%
Ataxia08.01.02.004; 17.02.02.0010.000804%
Axonal neuropathy17.09.03.0150.000268%Not Available
Cardio-respiratory arrest02.03.04.002; 22.02.06.0070.000179%Not Available
Coma17.02.09.0010.000179%Not Available
Confusional state17.02.03.005; 19.13.01.0010.000357%
Cyanosis23.06.04.005; 02.11.04.004; 24.03.01.007; 22.02.02.0070.000179%
Demyelination17.16.02.0010.000536%Not Available
Depression19.15.01.0010.000268%
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Drug abuse19.07.06.0100.005537%Not Available
Drug dependence19.07.06.0110.000536%Not Available
Dysaesthesia17.02.06.003; 23.03.03.0770.000357%
Epistaxis24.07.01.005; 22.04.03.0010.000179%
Euphoric mood19.04.02.006--
Feeling abnormal08.01.09.014--Not Available
Gait disturbance15.03.05.013; 08.01.02.002; 17.02.05.0160.000893%
Gastrointestinal pain07.01.05.0050.000179%
Headache17.14.01.001--
Hypoaesthesia23.03.03.081; 17.02.06.0230.000982%Not Available
Hypotension24.06.03.002--
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