Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Macular hole
ADR ID BADD_A04983
ADR Hierarchy
06      Eye disorders
06.09      Ocular structural change, deposit and degeneration NEC
06.09.03      Retinal structural change, deposit and degeneration
06.09.03.009      Macular hole
Description Perforations through the whole thickness of the retina including the macula as the result of inflammation, trauma, degeneration, etc. The concept includes retinal breaks, tears, dialyses, and holes. [MeSH]
MedDRA Code 10051058
MeSH ID D012167
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Macular hole | Lamellar macular hole | Macular foramen | Retinal Perforations | Perforation, Retinal | Perforations, Retinal | Retinal Perforation | Retinal Holes | Hole, Retinal | Holes, Retinal | Retinal Hole | Retinal Dialyses | Dialyses, Retinal | Retinal Dialyse | Retinal Tears | Retinal Tear | Tear, Retinal | Tears, Retinal | Retinal Breaks | Break, Retinal | Breaks, Retinal | Retinal Break | Macular Holes | Hole, Macular | Holes, Macular | Macular Hole
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000044%
BADD_D00151Apixaban0.000043%
BADD_D00285Bosentan0.000120%
BADD_D00623Dexamethasone0.000654%
BADD_D00898Finasteride0.000202%
BADD_D01251Latanoprost0.000112%
BADD_D01257Letrozole0.000790%
BADD_D01594Ocriplasmin--
BADD_D01771Pilocarpine hydrochloride--
BADD_D01954Rivaroxaban0.000063%
BADD_D02407Upadacitinib0.000241%
BADD_D02464Fingolimod0.000482%
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