Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Cystoid macular oedema
ADR ID BADD_A05565
ADR Hierarchy
06      Eye disorders
06.04      Ocular infections, irritations and inflammations
06.04.06      Retinal, choroid and vitreous infections and inflammations
06.04.06.010      Cystoid macular oedema
12      Injury, poisoning and procedural complications
12.02      Procedural related injuries and complications NEC
12.02.02      Eye and ear procedural complications
12.02.02.005      Cystoid macular oedema
Description Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90) | Fluid accumulation in the outer layer of the MACULA LUTEA at the center of the RETINA in a petaloid pattern where cystic spaces are formed and may lead to macular depressions or holes. [MeSH]
MedDRA Code 10058202
MeSH ID D008269
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cystoid macular edema | Aphakic cystoid macular edema | Aphakic cystoid macular oedema | Cystoid macular oedema | Irvine-Gass syndrome | Cystoid maculopathy | Macular Edema | Edema, Macular | Irvine-Gass Syndrome | Irvine Gass Syndrome | Syndrome, Irvine-Gass | Cystoid Macular Edema, Postoperative | Macular Edema, Cystoid | Edema, Cystoid Macular | Cystoid Macular Dystrophy | Macular Dystrophy, Dominant Cystoid | Central Retinal Edema, Cystoid | Cystoid Macular Edema
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000064r,6r-dorzolamide--
BADD_D00066Alendronic acid0.000044%
BADD_D00142Anastrozole0.001907%
BADD_D00274Bimatoprost0.001687%
BADD_D00300Bromfenac0.000541%
BADD_D00349Capecitabine0.000112%
BADD_D00364Carboplatin0.000168%
BADD_D00407Cefuroxime0.000930%
BADD_D00475Citalopram0.000029%
BADD_D00560Cytarabine0.000112%
BADD_D00623Dexamethasone0.000654%
BADD_D00699Docetaxel--
BADD_D00712Dorzolamide0.000531%
BADD_D00924Fluocinolone acetonide0.001001%
BADD_D01103Hydroxychloroquine0.003719%
BADD_D01119Ibrutinib0.000728%
BADD_D01232Ketorolac0.000213%
BADD_D01233Ketorolac tromethamine--
BADD_D01251Latanoprost0.000315%
BADD_D01257Letrozole0.000527%
BADD_D01317Loratadine0.000145%
BADD_D01401Metformin0.000011%
BADD_D01478Mitomycin0.000112%
BADD_D01555Nepafenac0.003293%
BADD_D01563Nicotinate--
BADD_D01594Ocriplasmin--
BADD_D01653Paclitaxel0.003134%
BADD_D01832Prednisolone acetate0.004318%
BADD_D01951Risperidone0.000606%
BADD_D02010Sertraline0.000038%
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