Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Muscle contracture
ADR ID BADD_A06120
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.03      Musculoskeletal and connective tissue disorders NEC
15.03.05      Musculoskeletal and connective tissue conditions NEC
15.03.05.024      Muscle contracture
Description A type of permanent damage to muscles and nerves that results from prolonged lack blood flow to those tissues. It is characterized by shortening and stiffening of the muscles. [MeSH]
MedDRA Code 10062575
MeSH ID D054061; D003286
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Post-traumatic muscle contracture | Volkmann's ischaemic contracture | Volkmann's ischemic contracture | Contractures NOS | Post poliomyelitic contracture | Contracture | Muscle contracture | Ischemic Contracture | Contracture, Ischemic | Contractures, Ischemic | Ischemic Contractures | Volkmann Contracture | Volkmann's Ischemic Contracture | Contracture, Volkmann's Ischemic | Ischemic Contracture, Volkmann's | Volkmann Ischemic Contracture | Volkmanns Ischemic Contracture | Contracture, Volkmann | Contractures, Volkmann | Volkmann Contractures
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00165Aripiprazole0.000079%
BADD_D00209Baclofen0.000362%
BADD_D00354Captopril--
BADD_D00477Citric acid0.000413%
BADD_D00549Cyclophosphamide--
BADD_D00571Dactinomycin--
BADD_D00809Escitalopram0.000028%
BADD_D00873Fenofibrate0.000079%
BADD_D00912Fluconazole--
BADD_D00967Fosinopril--
BADD_D00981Gabapentin--
BADD_D00985Gadodiamide0.007113%
BADD_D00989Gadolinium--
BADD_D00992Gadoterate meglumine--
BADD_D01250Lasofoxifene--
BADD_D01275Levofloxacin0.000211%
BADD_D01285Levothyroxine0.000010%
BADD_D01322Losartan0.000022%
BADD_D01405Methadone0.000265%
BADD_D01418Methotrexate--
BADD_D01442Metoclopramide0.000294%
BADD_D01477Misoprostol0.000925%
BADD_D01599Olanzapine0.000526%
BADD_D01602Olmesartan0.000524%
BADD_D01633Oxaliplatin0.000582%
BADD_D01656Paliperidone0.003005%
BADD_D01679Paroxetine0.000043%
BADD_D01831Prednisolone0.000077%
BADD_D01835Pregabalin0.000078%
BADD_D01840Primidone--
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