Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Infusion site reactions
ADR ID BADD_A06526
ADR Hierarchy
08      General disorders and administration site conditions
08.02      Administration site reactions
08.02.05      Infusion site reactions
12      Injury, poisoning and procedural complications
12.07      Administration site reactions
12.07.05      Infusion site reactions
Description Adverse reactions that occur initially at the site of injection or infusion. Milder type is confined to a local allergic flare reaction. A more severe reaction is caused by extravasation of VESICANTS from the blood vessel at the site of injection and can cause damage to the surrounding tissue. In tumor flare reaction symptoms involve well beyond the injection site such as an increase in the tumor size and tumor markers levels, bone pain, and HYPERCALCEMIA. [MeSH]
MedDRA Code 10068753
MeSH ID D000075662
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Injection Site Reaction | Injection Site Reactions | Injection Site Event | Injection Site Events | Injection Site Adverse Event | Infusion Site Reaction | Infusion Site Reactions | Infusion Site Adverse Reaction | Infusion Site Adverse Event
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00377Caspofungin acetate--
BADD_D00389Cefoperazone--
BADD_D00398Ceftaroline fosamil--
BADD_D00404Ceftobiprole--
BADD_D00405Ceftriaxone0.036989%
BADD_D00410Celecoxib0.000134%
BADD_D00417Cetirizine0.000146%
BADD_D00471Ciprofloxacin--
BADD_D00474Cisplatin0.000929%
BADD_D00479Cladribine--
BADD_D00482Clevidipine0.000228%
BADD_D00504Clopidogrel0.000021%
BADD_D00526Conivaptan--
BADD_D00527Conivaptan hydrochloride--
BADD_D00549Cyclophosphamide--
BADD_D00559Cysteine hydrochloride--
BADD_D00560Cytarabine0.000112%
BADD_D00577Dantrolene sodium--
BADD_D00581Daptomycin0.000248%
BADD_D00596Deferoxamine0.004213%
BADD_D00609Deoxycholic acid--
BADD_D00620Desoximetasone--
BADD_D00629Dexmedetomidine0.000732%
BADD_D00633Dexrazoxane--
BADD_D00674Diltiazem--
BADD_D00680Dimethyl fumarate0.000400%
BADD_D00686Diphenhydramine0.004970%
BADD_D00699Docetaxel--
BADD_D00723Doxorubicin0.000884%
BADD_D00782Epinephrine0.000081%
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ADReCS-Target
ADR Term Drug Name Target