Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Posterior reversible encephalopathy syndrome
ADR ID BADD_A06644
ADR Hierarchy
17      Nervous system disorders
17.13      Encephalopathies
17.13.02      Encephalopathies NEC
17.13.02.007      Posterior reversible encephalopathy syndrome
Description A condition that is characterized by HEADACHE; SEIZURES; and visual loss with edema in the posterior aspects of the CEREBRAL HEMISPHERES, such as the BRAIN STEM. Generally, lesions involve the white matter (nerve fibers) but occasionally the grey matter (nerve cell bodies). [MeSH]
MedDRA Code 10071066
MeSH ID D054038
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Reversible posterior leukoencephalopathy syndrome | Posterior reversible encephalopathy syndrome | Posterior Leukoencephalopathy Syndrome | Leukoencephalopathy Syndromes, Posterior | Syndrome, Posterior Leukoencephalopathy | Syndromes, Posterior Leukoencephalopathy | Leukoencephalopathy Syndrome, Posterior | Reversible Posterior Leukoencephalopathy Syndrome | Posterior Reversible Encephalopathy Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00775Enzalutamide0.002002%
BADD_D00809Escitalopram0.000038%
BADD_D00854Etoposide0.000336%
BADD_D00858Everolimus0.000382%
BADD_D00899Fingolimod hydrochloride--
BADD_D00914Fludarabine0.001063%
BADD_D00931Fluorouracil0.002298%
BADD_D00981Gabapentin0.000052%
BADD_D01009Gemcitabine0.000224%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01046Guanfacine0.000173%
BADD_D01103Hydroxychloroquine0.001859%
BADD_D01133Ifosfamide0.000112%
BADD_D01197Iron0.000453%
BADD_D01204Isoniazid0.002780%
BADD_D01223Ixazomib--
BADD_D01243Lamotrigine0.000221%
BADD_D01252Leflunomide0.001500%
BADD_D01254Lenvatinib0.000895%
BADD_D01258Leucovorin0.001859%
BADD_D01265Levetiracetam0.000278%
BADD_D01271Levocarnitine0.004312%
BADD_D01275Levofloxacin0.000063%
BADD_D01295Linezolid0.002470%
BADD_D01303Lithium carbonate0.000803%
BADD_D01304Lithium cation0.000384%
BADD_D01376Melphalan0.000112%
BADD_D01405Methadone0.002784%
BADD_D01433Methylprednisolone0.000304%
BADD_D01449Metronidazole0.000053%
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