Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Granulomatosis with polyangiitis
ADR ID BADD_A06686
ADR Hierarchy
10      Immune system disorders
10.02      Immune disorders NEC
10.02.02      Vasculitides
10.02.02.018      Granulomatosis with polyangiitis
20      Renal and urinary disorders
20.05      Nephropathies
20.05.01      Glomerulonephritis and nephrotic syndrome
20.05.01.013      Granulomatosis with polyangiitis
22      Respiratory, thoracic and mediastinal disorders
22.01      Lower respiratory tract disorders (excl obstruction and infection)
22.01.01      Lower respiratory tract inflammatory and immunologic conditions
22.01.01.015      Granulomatosis with polyangiitis
24      Vascular disorders
24.12      Vascular infections and inflammations
24.12.04      Vasculitides NEC
24.12.04.011      Granulomatosis with polyangiitis
Description A multisystemic disease of a complex genetic background. It is characterized by inflammation of the blood vessels (VASCULITIS) leading to damage in any number of organs. The common features include granulomatous inflammation of the RESPIRATORY TRACT and KIDNEYS. Most patients have measurable autoantibodies (ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES) against MYELOBLASTIN. [MeSH]
MedDRA Code 10072579
MeSH ID D014890
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Necrotizing granulomatous vasculitis | Wegener's granulomatosis | Wegeners granulomatosis | Necrotising granulomatous vasculitis | Refractory Wegener's granulomatosis | Granulomatosis with polyangiitis | Granulomatous polyangiitis | Granulomatosis with Polyangiitis | Granulomatosis with Polyangiitides | Polyangiitides, Granulomatosis with | Polyangiitis, Granulomatosis with | with Polyangiitides, Granulomatosis | with Polyangiitis, Granulomatosis | Wegener Granulomatosis | Granulomatosis, Wegener | Wegener's Granulomatosis | Granulomatosis, Wegener's
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00103Amikacin0.000338%
BADD_D00129Amoxicillin0.000007%
BADD_D00195Azathioprine0.000470%
BADD_D00318Busulfan--
BADD_D00549Cyclophosphamide--
BADD_D00563Dabigatran0.000245%
BADD_D01096Hydromorphone0.000185%
BADD_D01213Isotretinoin0.001029%
BADD_D01260Leuprolide acetate0.001434%
BADD_D01275Levofloxacin0.000232%
BADD_D01397Mesalamine0.000274%
BADD_D01831Prednisolone0.000035%
BADD_D01834Prednisone0.000022%
BADD_D01869Propylthiouracil0.018808%
BADD_D02093Sulfasalazine0.000455%
BADD_D02375Water--
BADD_D02464Fingolimod--
BADD_D02577Oseltamivir acid0.000372%
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