Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Peripheral venous disease
ADR ID BADD_A06771
ADR Hierarchy
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.02      Non-site specific necrosis and vascular insufficiency NEC
24.04.02.022      Peripheral venous disease
Description Impaired venous blood flow or venous return (venous stasis), usually caused by inadequate venous valves. Venous insufficiency often occurs in the legs, and is associated with EDEMA and sometimes with VENOUS STASIS ULCERS at the ankle. [MeSH]
MedDRA Code 10075049
MeSH ID D014689
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Venostasis | Venous (peripheral) insufficiency, unspecified | Venous stasis | Venous insufficiency | Venous oedema | Venous edema | Chronic venous insufficiency | Hypostasis | Venous reflux | Venous valvular incompetency | Peripheral venous disease | Venous peripheral insufficiency | Superficial venous reflux disease | Venous reflux disorder | Venous Insufficiency | Insufficiencies, Venous | Insufficiency, Venous | Venous Insufficiencies
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00066Alendronic acid0.000616%
BADD_D00073Aliskiren0.000609%
BADD_D00151Apixaban0.000291%
BADD_D00165Aripiprazole0.000119%
BADD_D00284Bortezomib--
BADD_D00786Eplerenone0.007424%
BADD_D00809Escitalopram0.000028%
BADD_D00898Finasteride0.000045%
BADD_D01250Lasofoxifene--
BADD_D01336Macitentan0.000265%
BADD_D01401Metformin0.000005%
BADD_D01418Methotrexate--
BADD_D01428Methylergonovine0.002243%
BADD_D01567Nilotinib0.000280%
BADD_D01570Nisoldipine--
BADD_D01654Palbociclib0.000112%
BADD_D01668Pantoprazole0.000041%
BADD_D01834Prednisone0.000009%
BADD_D01835Pregabalin0.000202%
BADD_D01954Rivaroxaban0.000234%
BADD_D01961Rofecoxib--
BADD_D02031Sitaxentan--
BADD_D02104Tacrine hydrochloride--
BADD_D02107Tafamidis0.001615%
BADD_D02170Testosterone0.000227%
BADD_D02174Testosterone undecanoate--
BADD_D02236Tofacitinib0.001591%
BADD_D02329Valproic acid0.000100%
BADD_D02346Venlafaxine--
BADD_D02373Warfarin0.000042%
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