Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Multiple organ dysfunction syndrome
ADR ID BADD_A06819
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.057      Multiple organ dysfunction syndrome
Description A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [MeSH]
MedDRA Code 10077361
MeSH ID D009102
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
MOF | Multi organ failure | Multi-organ failure | Multiorgan failure | Multiple organ failure | Multiple organ dysfunction syndrome | Multiple Organ Failure | Multiple Organ Dysfunction Syndrome | Organ Failure, Multiple | Failure, Multiple Organ | Multiple Organ Failures | MODS | Organ Dysfunction Syndrome, Multiple
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00347Candesartan cilexetil0.000841%
BADD_D00349Capecitabine0.001847%
BADD_D00356Carbamazepine0.001116%
BADD_D00364Carboplatin0.000616%
BADD_D00367Carfilzomib0.000504%
BADD_D00368Carglumic acid0.008625%
BADD_D00376Caspofungin0.000523%
BADD_D00386Cefepime0.000146%
BADD_D00405Ceftriaxone0.060163%
BADD_D00407Cefuroxime0.000501%
BADD_D00410Celecoxib0.000224%
BADD_D00412Cephalexin0.000017%
BADD_D00414Ceritinib0.000224%
BADD_D00440Chloroquine0.000283%
BADD_D00469Cinacalcet hydrochloride--
BADD_D00474Cisplatin0.000783%
BADD_D00479Cladribine0.000229%
BADD_D00495Clofarabine0.000168%
BADD_D00501Clonazepam0.000074%
BADD_D00504Clopidogrel0.000267%
BADD_D00511Clozapine--
BADD_D00518Colchicine0.000244%
BADD_D00545Cyclobenzaprine0.000064%
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine0.001050%
BADD_D00560Cytarabine0.002071%
BADD_D00563Dabigatran0.011866%
BADD_D00571Dactinomycin0.000224%
BADD_D00580Dapsone0.001650%
BADD_D00581Daptomycin0.000389%
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