Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Multiple organ dysfunction syndrome
ADR ID BADD_A06819
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.03      General signs and symptoms NEC
08.01.03.057      Multiple organ dysfunction syndrome
Description A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative. [MeSH]
MedDRA Code 10077361
MeSH ID D009102
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
MOF | Multi organ failure | Multi-organ failure | Multiorgan failure | Multiple organ failure | Multiple organ dysfunction syndrome | Multiple Organ Failure | Multiple Organ Dysfunction Syndrome | Organ Failure, Multiple | Failure, Multiple Organ | Multiple Organ Failures | MODS | Organ Dysfunction Syndrome, Multiple
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01942Riluzole0.000808%
BADD_D01951Risperidone0.001818%
BADD_D01954Rivaroxaban--
BADD_D01955Rivastigmine0.001626%
BADD_D01959Rocuronium0.000085%
BADD_D01964Romidepsin--
BADD_D01971Rosuvastatin0.000060%
BADD_D01978Ruxolitinib0.000755%
BADD_D02026Simvastatin0.000033%
BADD_D02028Sirolimus0.000938%
BADD_D02031Sitaxentan--
BADD_D02034Sodium bicarbonate0.000427%
BADD_D02053Sofosbuvir0.002964%
BADD_D02058Sorafenib0.000918%
BADD_D02066Spironolactone0.000128%
BADD_D02100Sunitinib0.003078%
BADD_D02105Tacrolimus0.009654%
BADD_D02107Tafamidis0.001346%
BADD_D02136Tedizolid phosphate-
BADD_D02143Telavancin--
BADD_D02145Telbivudine--
BADD_D02160Terbinafine0.000447%
BADD_D02192Thalidomide0.001326%
BADD_D02203Thiotepa--
BADD_D02217Tigecycline0.000146%
BADD_D02246Tolvaptan0.000320%
BADD_D02253Trabectedin0.000224%
BADD_D02254Tramadol0.000051%
BADD_D02257Trametinib0.000280%
BADD_D02261Tranexamic acid0.006235%
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