| ADR Ontology |
| ADR Term |
Astrocytoma malignant |
| ADR ID |
BADD_A09506 |
| ADR Hierarchy |
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| Description |
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) [MeSH] |
| MedDRA Code |
10060971 |
| MeSH ID |
D001254
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Anaplastic astrocytoma | Astrocytoma malignant NOS | Cerebellar astrocytoma | Cerebral astrocytoma, high grade | Astrocytoma malignant | Anaplastic pleomorphic xanthoastrocytoma | High grade astrocytoma with piloid features | High grade pleomorphic xanthoastrocytoma | IDH-mutant astrocytoma with homozygous CDK2NA/B deletion | Astrocytoma | Astrocytomas | Astroglioma | Astrogliomas | Glioma, Astrocytic | Astrocytic Glioma | Astrocytic Gliomas | Gliomas, Astrocytic | Astrocytoma, Grade I | Astrocytomas, Grade I | Grade I Astrocytoma | Grade I Astrocytomas | Astrocytoma, Grade II | Astrocytomas, Grade II | Grade II Astrocytoma | Grade II Astrocytomas | Astrocytoma, Protoplasmic | Astrocytomas, Protoplasmic | Protoplasmic Astrocytoma | Protoplasmic Astrocytomas | Astrocytoma, Subependymal Giant Cell | Subependymal Giant Cell Astrocytoma | Pilocytic Astrocytoma | Astrocytoma, Pilocytic | Astrocytomas, Pilocytic | Pilocytic Astrocytomas | Childhood Cerebral Astrocytoma | Astrocytoma, Childhood Cerebral | Astrocytomas, Childhood Cerebral | Cerebral Astrocytoma, Childhood | Cerebral Astrocytomas, Childhood | Childhood Cerebral Astrocytomas | Fibrillary Astrocytoma | Astrocytoma, Fibrillary | Astrocytomas, Fibrillary | Fibrillary Astrocytomas | Gemistocytic Astrocytoma | Astrocytoma, Gemistocytic | Astrocytomas, Gemistocytic | Gemistocytic Astrocytomas | Intracranial Astrocytoma | Astrocytoma, Intracranial | Astrocytomas, Intracranial | Intracranial Astrocytomas | Juvenile Pilocytic Astrocytoma | Astrocytoma, Juvenile Pilocytic | Astrocytomas, Juvenile Pilocytic | Juvenile Pilocytic Astrocytomas | Pilocytic Astrocytoma, Juvenile | Pilocytic Astrocytomas, Juvenile | Oligoastrocytoma, Mixed | Mixed Oligoastrocytoma | Mixed Oligoastrocytomas | Oligoastrocytomas, Mixed | Anaplastic Astrocytoma | Anaplastic Astrocytomas | Astrocytoma, Anaplastic | Astrocytomas, Anaplastic | Astrocytoma, Grade III | Astrocytomas, Grade III | Grade III Astrocytoma | Grade III Astrocytomas | Cerebral Astrocytoma | Astrocytoma, Cerebral | Astrocytomas, Cerebral | Cerebral Astrocytomas |
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| Drugs Leading to the ADR |
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