Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acebutolol
Drug ID BADD_D00019
Description A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Indications and Usage For the management of hypertension and ventricular premature beats in adults.
Marketing Status approved; investigational
ATC Code C07AB04
DrugBank ID DB01193
KEGG ID D02338
MeSH ID D000070
PubChem ID 1978
TTD Drug ID D0HD9K
NDC Product Code Not Available
UNII 67P356D8GH
Synonyms Acebutolol | Acetobutolol | Acebutolol Hydrochloride | M&B-17803 A | M&B 17803 A | M&B17803 A | M & B 17803A | Neptal | Prent | Rhotral | Sectral | Monitan | Apo-Acebutolol | Apo Acebutolol | ApoAcebutolol | Novo-Acebutolol | Novo Acebutolol | NovoAcebutolol
Chemical Information
Molecular Formula C18H28N2O4
CAS Registry Number 37517-30-9
SMILES CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dermatitis23.03.04.002--Not Available
Dermatitis exfoliative23.03.07.001; 10.01.01.004--
Diarrhoea07.02.01.001--
Discomfort08.01.08.003--Not Available
Disorientation17.02.05.015; 19.13.01.002--Not Available
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dry eye06.08.02.001--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Dysuria20.02.02.002--
Eye pain06.08.03.002--
Fatigue08.01.01.002--
Feeling abnormal08.01.09.014--Not Available
Flatulence07.01.04.002--
Flushing23.06.05.003; 08.01.03.025; 24.03.01.002--
Gait disturbance15.03.05.013; 17.02.05.016; 08.01.02.002--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Hallucination19.10.04.003--
Headache17.14.01.001--
Hyperhidrosis23.02.03.004; 08.01.03.028--
Hypertension24.08.02.001--
Hypoaesthesia23.03.03.081; 17.02.06.023--Not Available
Hypotension24.06.03.002--
Insomnia19.02.01.002; 17.15.03.002--
Intermittent claudication24.04.03.001--Not Available
Laryngeal oedema22.04.02.001; 10.01.05.003; 23.04.01.005--
Laryngospasm22.04.02.002--
Lethargy17.02.04.003; 19.04.04.004; 08.01.01.008--
Loss of consciousness17.02.04.004--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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