Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Albendazole
Drug ID BADD_D00052
Description A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)
Indications and Usage For the treatment of parenchymal neurocysticercosis due to active lesions caused by larval forms of the pork tapeworm, Taenia solium and for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus.
Marketing Status approved; vet_approved
ATC Code P02CA03
DrugBank ID DB00518
KEGG ID D00134
MeSH ID D015766
PubChem ID 2082
TTD Drug ID D00KVO
NDC Product Code 49452-0003; 51927-1763; 52286-0001; 63629-1221; 64896-693; 60592-002; 42799-110; 43598-452; 69539-151; 52286-5500; 42291-093; 69097-237; 69766-026; 0115-1701; 53104-7736; 31722-935; 51407-258; 63629-9278; 72205-051; 0591-2712; 51927-0068; 72643-008; 86055-0004; 73309-129; 70710-1021; 70771-1103; 78482-110
UNII F4216019LN
Synonyms Albendazole | Lurdex | Bilutac | Metiazol | Andazol | Albenza | Zentel | Albendoral | Albendazole Monohydrochloride | Monohydrochloride, Albendazole | Bendapar | Digezanol | Disthelm | Mediamix V Disthelm | Endoplus | Eskazole | Gascop | SK&F-62979 | SK&F 62979 | SK&F62979 | SKF-62979 | SKF 62979 | SKF62979 | Valbazen
Chemical Information
Molecular Formula C12H15N3O2S
CAS Registry Number 54965-21-8
SMILES CCCSC1=CC2=C(C=C1)N=C(N2)NC(=O)OC
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nausea07.01.07.0010.006762%
Neutropenia01.02.03.0040.002536%Not Available
Ocular hyperaemia06.04.05.0040.002536%Not Available
Oedema14.05.06.010; 08.01.07.0060.001691%Not Available
Oedema peripheral02.05.04.007; 14.05.06.011; 08.01.07.0070.001691%
Pain in extremity15.03.04.0100.001691%
Pallor24.03.04.001; 23.03.03.031; 08.01.03.0320.002536%Not Available
Palpitations02.11.04.0120.001691%
Pancytopenia01.03.03.0030.005072%Not Available
Premature baby18.04.02.0010.001691%Not Available
Premature delivery18.07.01.0060.004226%
Pruritus23.03.12.0010.016398%
Pyrexia08.05.02.0030.024006%
Rash23.03.13.0010.008791%Not Available
Rectal haemorrhage24.07.02.018; 07.12.03.0010.001691%
Rhabdomyolysis15.05.05.002--
Seizure17.12.03.0010.002536%
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.0030.001691%Not Available
Skin hyperpigmentation23.05.01.0030.001691%
Skin ulcer24.04.03.007; 23.07.03.0030.005072%
Somnolence19.02.05.003; 17.02.04.006--
Stevens-Johnson syndrome11.07.01.005; 10.01.01.045; 23.03.01.007; 12.03.01.0140.003381%
Syncope02.11.04.015; 24.06.02.012; 17.02.04.0080.003381%
Tachycardia02.03.02.0070.005072%Not Available
Testicular swelling21.13.01.0030.001691%Not Available
Thrombocytopenia01.08.01.002--Not Available
Tongue ulceration07.14.01.0030.001691%Not Available
Toxic encephalopathy17.13.01.004; 12.03.01.0270.001691%Not Available
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.0060.007607%
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