| Pharmaceutical Information |
| Drug Name |
Bleomycin |
| Drug ID |
BADD_D00280 |
| Description |
A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0). It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin. |
| Indications and Usage |
For palliative treatment in the management malignant neoplasm (trachea, bronchus, lung), squamous cell carcinoma, and lymphomas. |
| Marketing Status |
approved; investigational |
| ATC Code |
L01DC01 |
| DrugBank ID |
DB00290
|
| KEGG ID |
D07535
|
| MeSH ID |
D001761
|
| PubChem ID |
5460769
|
| TTD Drug ID |
D06UVD
|
| NDC Product Code |
0143-9241; 69097-364; 0703-3155; 0143-9240; 16714-908; 61703-332; 61703-323; 16714-886; 0409-0332; 70121-1567; 0409-0323; 0703-3154 |
| UNII |
40S1VHN69B
|
| Synonyms |
Bleomycin | Bleomycins | BLEO-cell | BLEO cell | BLEOcell | Bleolem | Bléomycine Bellon | Bellon, Bléomycine | Bleomycin A2 | Bleomycin A(2) | Bleomycin B2 | Bleomycin B(2) | Bleomycin Sulfate | Sulfate, Bleomycin | Bleomycinum Mack | Mack, Bleomycinum | Blenoxane | Blanoxan | Bleomicina |
|
| Chemical Information |
| Molecular Formula |
C55H84N17O21S3+ |
| CAS Registry Number |
11056-06-7 |
| SMILES |
CC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)
OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6
=NC(=CS6)C(=O)NCCC[S+](C)C)O |
| Chemical Structure |
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| ADRs Induced by Drug |
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