Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Bromfenac
Drug ID BADD_D00300
Description Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation. Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool to optimize surgical outcomes.
Indications and Usage For the treatment of postoperative inflammation in patients who have undergone cataract extraction.
Marketing Status approved
ATC Code S01BC11
DrugBank ID DB00963
KEGG ID D07541
MeSH ID C053083
PubChem ID 60726
TTD Drug ID D0U1OM
NDC Product Code 65862-789; 49708-754; 68083-313; 50383-249; 72266-142
UNII 864P0921DW
Synonyms bromfenac | ISV-303 | Duract | sodium bromfenac | bromfenac sodium | Xibrom | AHR-10282
Chemical Information
Molecular Formula C15H12BrNO3
CAS Registry Number 91714-94-2
SMILES C1=CC(=C(C(=C1)C(=O)C2=CC=C(C=C2)Br)N)CC(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Skin disorder23.03.03.007--Not Available
Swelling face10.01.05.018; 08.01.03.100; 23.04.01.018--Not Available
Vision blurred17.17.01.010; 06.02.06.007--
Visual acuity reduced06.02.10.012; 17.17.01.011--
Visual impairment06.02.10.0130.000596%Not Available
Conjunctival hyperaemia06.04.01.004--Not Available
Eye pruritus06.04.05.006--Not Available
Ocular discomfort06.08.03.0080.000921%Not Available
Eyelid bleeding24.07.05.010; 23.06.07.005; 06.07.05.001--Not Available
Corneal thinning06.06.03.009--Not Available
Anterior chamber inflammation06.04.10.002--Not Available
Cystoid macular oedema06.04.06.010; 12.02.02.0050.000541%Not Available
Scleromalacia06.09.06.005--Not Available
Mediastinal disorder22.09.03.001--Not Available
Corneal disorder06.08.01.004--Not Available
Sensation of foreign body08.01.09.002--Not Available
Sinus operation25.05.05.001--Not Available
Ulcerative keratitis10.02.01.021; 06.04.02.0040.002247%
Treatment failure08.06.01.0170.001381%Not Available
Swelling of eyelid23.04.01.026; 10.01.05.026; 06.04.04.0180.001841%Not Available
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