Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Budesonide
Drug ID BADD_D00306
Description Budesonide is a glucocorticoid that is a mix of the 22R and 22S epimer used to treat inflammatory conditions of the lungs and intestines such as asthma, COPD, Crohn's disease, and ulcerative colitis.[A188529,A188532] Budesonide was granted FDA approval on 14 February 1994.[L10598]
Indications and Usage The oral capsule is used for the treatment of mild to moderate active Crohn's disease. The oral tablet is used for induction of remission in patients with active, mild to moderate ulcerative colitis. The oral inhalation formulation is used for the treatment of asthma, non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis.
Marketing Status Prescription; OTC; Discontinued
ATC Code A07EA06; D07AC09; R01AD05; R03BA02
DrugBank ID DB01222
KEGG ID D00246
MeSH ID D019819
PubChem ID 5281004
TTD Drug ID D0Y7IU
NDC Product Code 0574-9850; 60505-6129; 0093-6815; 60687-596; 46122-389; 38779-3097; 21130-710; 60870-0466; 0093-6817; 0093-6816; 55566-1002; 49076-6111; 0363-0048; 51407-366; 0904-7166; 65162-778; 52128-133; 0591-2510; 0186-1988; 0186-1990; 51862-580; 0378-4500; 0487-9601; 47335-631; 63629-8294; 0781-7516; 15308-0100; 51508-004; 68788-7290; 0378-7155; 16714-018; 65089-0005; 52221-117; 76282-641; 81749-004; 49452-1292; 46439-8719; 60505-0839; 16714-829; 55154-4849; 65089-0024; 69097-318; 0574-9855; 68382-720; 65649-651; 76282-640; 38779-0198; 69097-321; 16714-020; 0115-1687; 76282-642; 55566-1020; 69842-001; 60429-264; 64918-0205; 49927-0004; 0186-1989; 10695-124; 50090-2239; 50580-646; 60505-6194; 71052-270; 51079-020; 51407-128; 68682-309; 0186-0916; 49452-1291; 16714-019; 68788-7314; 70771-1075; 68012-309; 0781-7517; 63592-0187; 0487-9701; 11822-1700; 50546-580; 63190-0060; 49035-703; 53183-6310; 53104-7617; 68743-309; 0781-7515; 73377-076; 47335-633; 0115-1689; 64918-0204; 69097-319; 0536-1112; 66412-0393; 51552-1365; 46439-8737; 68981-017; 47335-632; 0186-0917; 64980-255
Synonyms Budesonide | Budesonide, (S)-Isomer | Pulmicort | Rhinocort | Budesonide, (R)-Isomer | Horacort
Chemical Information
Molecular Formula C25H34O6
CAS Registry Number 51333-22-3
SMILES CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Cholangitis09.02.01.0020.000406%Not Available
Chronic obstructive pulmonary disease22.03.01.0070.000636%Not Available
Coagulopathy01.01.02.001--Not Available
Cold sweat08.01.03.024; 23.02.03.0020.000406%Not Available
Colitis07.08.01.0010.000609%
Colitis ulcerative10.02.01.004; 07.08.01.0050.001016%Not Available
Confusional state19.13.01.001; 17.02.03.005--
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Cough22.02.03.0010.007110%
Crohn's disease10.02.01.005; 07.08.01.0150.005891%Not Available
Crying12.02.11.001; 08.01.03.005; 19.04.02.002; 17.02.05.0130.000406%Not Available
Cushing's syndrome19.07.03.002; 14.11.01.007; 05.01.01.001; 24.08.04.0010.003250%Not Available
Cushingoid24.08.02.004; 19.07.03.001; 14.11.01.006; 05.01.01.0020.002844%
Cyanosis24.03.01.007; 22.02.02.007; 02.01.02.0020.002031%
Cytomegalovirus infection11.05.01.0020.000609%
Death08.04.01.001--
Dehydration14.05.05.0010.001625%
Delayed puberty21.03.02.014; 05.05.03.0030.000609%
Depression19.15.01.001--
Dermatitis23.03.04.002--Not Available
Dermatitis allergic23.03.04.003; 10.01.03.0140.000609%Not Available
Dermatitis contact23.03.04.004; 10.01.01.003; 12.03.01.0400.000406%Not Available
Diarrhoea07.02.01.001--
Diarrhoea haemorrhagic24.07.02.004; 07.02.01.0020.001219%Not Available
Discomfort08.01.08.0030.000813%Not Available
Disseminated intravascular coagulation24.01.01.010; 01.01.02.0020.000159%
Disseminated tuberculosis11.04.01.0010.000609%Not Available
Disturbance in attention19.21.02.002; 17.03.03.0010.000406%
Dizziness24.06.02.007; 17.02.05.003; 02.01.02.004--
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