Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Cevimeline
Drug ID BADD_D00424
Description Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.
Indications and Usage For the treatment of symptoms of dry mouth in patients with Sjögren's Syndrome.
Marketing Status approved
ATC Code N07AX03
DrugBank ID DB00185
KEGG ID D07667
MeSH ID C059240
PubChem ID 2684
TTD Drug ID D0Q4CS
NDC Product Code 64642-011; 63304-479
UNII K9V0CDQ56E
Synonyms cevimeline | 2-methyspiro(1,3-oxathiolane-5,3)quinuclidine | AF 102B, (trans)-isomer | AF-102B | AF 102B | AF102B | Evoxac | FKS 508 | FKS-508 | SNI 2011 | SNI-2011 | AF 102B, (cis-(+))-isomer | cevimeline hydrochloride
Chemical Information
Molecular Formula C10H17NOS
CAS Registry Number 124620-88-8
SMILES CC1OC2(CN3CCC2CC3)CS1
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Peptic ulcer07.04.07.001--Not Available
Pericarditis02.06.02.001--
Periodontal destruction11.01.04.008; 07.09.01.005--Not Available
Periorbital oedema23.04.01.002; 10.01.05.010; 06.08.03.017--
Peripheral ischaemia24.04.03.002--
Personality disorder19.05.02.002--Not Available
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Phlebitis superficial24.12.03.005--Not Available
Photopsia17.17.01.006; 06.02.06.004--
Photosensitivity reaction23.03.09.003--
Plantar fasciitis15.03.03.002--Not Available
Platelet disorder01.08.03.001--Not Available
Pleural effusion22.05.02.002--
Pleurisy22.05.01.001--Not Available
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pneumothorax22.05.02.003--
Pollakiuria20.02.02.007--
Polyuria20.02.03.002--Not Available
Proctalgia07.03.02.001--
Prostatic disorder21.04.01.001--Not Available
Pruritus23.03.12.001--
Pruritus genital23.03.12.008; 21.10.01.002--Not Available
Pulmonary congestion02.05.02.002; 24.03.08.001; 22.01.03.002--Not Available
Pulmonary embolism24.01.06.001; 22.06.02.001--Not Available
Pulmonary fibrosis22.01.02.006--
Purpura24.07.06.005; 23.06.01.004; 01.01.04.003--
Pyelonephritis20.01.09.001; 11.01.14.002--Not Available
Pyuria20.08.02.016; 11.01.08.043--Not Available
Rash23.03.13.0010.015547%Not Available
Rash erythematous23.03.13.029--Not Available
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