Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression, as indicated by the FDA label [FDA label]. Off-label indications include but are not limited to: treatment of sexual dysfunction, post-stroke behavioural changes, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label], [A321], [A322], [A323], [A324], [A174406], [A174409], [A174412].
Marketing Status approved
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 42806-020; 71335-0541; 76282-206; 80425-0093; 37662-0340; 43353-091; 54458-980; 0054-0062; 70518-2601; 63850-3616; 0456-4040; 68071-3034; 68788-7899; 70518-2228; 76282-207; 76282-629; 43353-112; 43353-208; 50090-5172; 50090-5175; 61919-390; 0378-6231; 69097-822; 69097-824; 71610-092; 37662-0341; 37662-0342; 52427-691; 65162-053; 0378-6233; 69097-823; 60429-175; 62135-540; 65162-052; 0378-6232; 70518-2553; 70518-2617; 70518-2671; 37662-0339; 37662-0343; 50090-5170; 51655-137; 60429-173; 60429-174; 61919-389; 0456-4020; 42806-021; 54458-889; 54458-981; 65162-054; 0456-4010; 76282-628; 37662-0337; 37662-0338; 42806-019; 51655-938; 71610-412; 71610-422; 76282-208; 37662-0336; 43063-063; 51655-209
UNII 0DHU5B8D6V
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Menstrual disorder21.01.01.004--Not Available
Mental disability26.01.01.001--Not Available
Mental impairment17.03.03.002; 19.21.02.0030.000029%Not Available
Metabolic acidosis14.01.01.0030.000019%Not Available
Micturition disorder20.02.02.005--Not Available
Middle insomnia19.02.01.003; 17.15.03.0030.000029%Not Available
Migraine24.03.05.003; 17.14.02.001--Not Available
Mood altered19.04.02.0070.000042%Not Available
Mood swings19.04.03.0010.000099%Not Available
Mouth ulceration07.05.06.004--Not Available
Multiple sclerosis17.16.01.001; 10.04.10.008--Not Available
Muscle contractions involuntary17.05.03.001; 15.05.03.0080.000029%Not Available
Muscle rigidity17.05.02.005; 15.05.04.0010.000029%Not Available
Muscle spasms15.05.03.004--
Muscle twitching15.05.03.0050.000061%Not Available
Muscular weakness17.05.03.005; 15.05.06.001--
Myalgia15.05.02.001--
Mydriasis06.05.03.004; 17.02.11.0030.000048%Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.008--Not Available
Myoclonus17.02.05.0080.000019%Not Available
Narcolepsy19.02.02.002; 17.15.01.0020.000067%Not Available
Nausea07.01.07.001--
Neck pain15.03.04.009--
Neonatal disorder18.04.01.0010.000029%Not Available
Neoplasm16.16.02.001--Not Available
Nephrolithiasis20.04.01.002--
Nervous system disorder17.02.10.001--Not Available
Nervousness19.06.02.0030.000019%Not Available
Neuralgia17.02.07.005--
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ADReCS-Target
Drug Name ADR Term Target
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