Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Citalopram
Drug ID BADD_D00475
Description Citalopram belongs to a class of antidepressant agents known as selective _serotonin-reuptake inhibitors_ (SSRIs) and is widely used to treat the symptoms of depression. Its chemical structure is unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other prescribed antidepressants [FDA label]. Citalopram is also known as _Celexa_, and available in tablet and solution forms [FDA label]. This drug was initially approved by the FDA in 1998 [L5230].
Indications and Usage For the treatment of depression, as indicated by the FDA label [FDA label]. Off-label indications include but are not limited to: treatment of sexual dysfunction, post-stroke behavioural changes, ethanol abuse, obsessive-compulsive disorder (OCD) in children, and diabetic neuropathy [FDA label], [A321], [A322], [A323], [A324], [A174406], [A174409], [A174412].
Marketing Status approved
ATC Code N06AB04
DrugBank ID DB00215
KEGG ID D07704
MeSH ID D015283
PubChem ID 2771
TTD Drug ID D0Y5DO
NDC Product Code 42806-020; 71335-0541; 76282-206; 80425-0093; 37662-0340; 43353-091; 54458-980; 0054-0062; 70518-2601; 63850-3616; 0456-4040; 68071-3034; 68788-7899; 70518-2228; 76282-207; 76282-629; 43353-112; 43353-208; 50090-5172; 50090-5175; 61919-390; 0378-6231; 69097-822; 69097-824; 71610-092; 37662-0341; 37662-0342; 52427-691; 65162-053; 0378-6233; 69097-823; 60429-175; 62135-540; 65162-052; 0378-6232; 70518-2553; 70518-2617; 70518-2671; 37662-0339; 37662-0343; 50090-5170; 51655-137; 60429-173; 60429-174; 61919-389; 0456-4020; 42806-021; 54458-889; 54458-981; 65162-054; 0456-4010; 76282-628; 37662-0337; 37662-0338; 42806-019; 51655-938; 71610-412; 71610-422; 76282-208; 37662-0336; 43063-063; 51655-209
UNII 0DHU5B8D6V
Synonyms Citalopram | Cytalopram | Citalopram Hydrobromide | Lu-10-171 | Lu10171 | Seropram | Celexa
Chemical Information
Molecular Formula C20H21FN2O
CAS Registry Number 59729-33-8
SMILES CN(C)CCCC1(C2=C(CO1)C=C(C=C2)C#N)C3=CC=C(C=C3)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Injection site swelling08.02.03.017; 12.07.03.0180.000129%Not Available
Affect lability19.04.01.0010.000019%Not Available
Skin burning sensation23.03.03.021; 17.02.06.0090.000042%Not Available
Cerebral disorder17.02.10.017--Not Available
Foetal death18.01.02.003; 08.04.01.0110.000019%
Haemorrhage24.07.01.002--Not Available
Cutaneous lupus erythematosus23.03.02.008; 15.06.02.007; 10.04.03.0070.000019%Not Available
Hypoaesthesia oral17.02.06.021; 07.05.05.003--Not Available
Breast cancer female21.05.01.011; 16.10.01.004--Not Available
Cognitive disorder19.21.02.001; 17.03.03.003--
Female sexual dysfunction19.08.05.001; 21.03.02.004--Not Available
Major depression19.15.01.0030.000019%Not Available
Dyslipidaemia14.08.04.0150.000065%Not Available
Pulseless electrical activity02.03.04.0200.000019%Not Available
Cystoid macular oedema12.02.02.005; 06.04.06.0100.000029%Not Available
Restless legs syndrome15.05.03.012; 17.02.07.008--Not Available
Disturbance in sexual arousal19.08.04.0030.000019%Not Available
Intestinal mass07.11.01.010--Not Available
Congenital eye disorder06.08.03.011; 03.01.01.002--Not Available
Blood alkaline phosphatase increased13.04.02.004--
Urine output increased13.13.03.002--Not Available
Hepatic enzyme increased13.03.04.028--Not Available
Hot flush21.02.02.001; 08.01.03.027; 24.03.01.0050.000074%
Bacterial infection11.02.01.005--Not Available
Blood test abnormal13.18.01.003--Not Available
Breast disorder21.05.04.004--Not Available
Cardiac disorder02.11.01.0030.000029%Not Available
Embolism24.01.01.009--
Malnutrition14.03.02.004--Not Available
Mental disorder19.07.01.002--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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