Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Citric acid
Drug ID BADD_D00477
Description A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability. Citric acid was one of active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020.[L14120]
Indications and Usage Not Available
Marketing Status approved; nutraceutical; vet_approved
ATC Code A09AB04
DrugBank ID DB04272
KEGG ID D01222
MeSH ID D019343
PubChem ID 311
TTD Drug ID D02RTS
NDC Product Code 81803-040
UNII XF417D3PSL
Synonyms Citric Acid | Citric Acid Monohydrate | Uralyt U | Citrate | Citric Acid, Anhydrous | Anhydrous Citric Acid
Chemical Information
Molecular Formula C6H8O7
CAS Registry Number 77-92-9
SMILES C(C(=O)O)C(CC(=O)O)(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Muscle twitching15.05.03.0050.004128%Not Available
Nausea07.01.07.0011.839044%
Neck pain15.03.04.0090.148070%
Pallor24.03.04.001; 23.03.03.031; 08.01.03.0321.693163%Not Available
Palpitations02.11.04.0120.167017%
Paraesthesia23.03.03.094; 17.02.06.0053.654477%
Peripheral coldness23.06.04.008; 24.04.03.006; 08.01.09.0100.005820%Not Available
Restlessness19.11.02.002; 17.02.05.0210.360701%
Tachypnoea22.02.01.0140.003220%Not Available
Tetany15.05.03.013; 14.04.01.005; 05.04.02.0030.024190%Not Available
Thirst14.03.02.007; 08.01.09.0210.901050%Not Available
Vision blurred17.17.01.010; 06.02.06.0070.779647%
Vomiting07.01.07.003--
Muscle tightness15.05.03.0070.004417%Not Available
Citrate toxicity12.03.01.043; 14.11.01.026--Not Available
Epigastric discomfort07.01.02.0040.001610%Not Available
Hypoaesthesia oral17.02.06.021; 07.05.05.0030.007430%Not Available
Paraesthesia oral07.05.05.035; 17.02.06.0080.010939%Not Available
Poisoning12.03.01.004--Not Available
Muscle contracture15.03.05.0240.000413%Not Available
Vessel puncture site haematoma24.07.01.018; 12.07.04.003; 08.02.04.0020.001404%Not Available
Gastrointestinal tract irritation07.08.03.008--Not Available
Pharyngeal swelling22.04.05.0280.000908%Not Available
Vessel puncture site erythema23.03.06.029; 12.07.04.036; 08.02.04.0360.001404%Not Available
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