Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Deferasirox
Drug ID BADD_D00594
Description Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Indications and Usage For the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older.
Marketing Status approved; investigational
ATC Code V03AC03
DrugBank ID DB01609
KEGG ID D03669
MeSH ID D000077588
PubChem ID 214348
TTD Drug ID D0Q5UQ
NDC Product Code 49706-2103; 59285-010; 66039-871; 31722-030; 43598-852; 45963-454; 45963-456; 67877-552; 69238-1703; 69452-161; 69539-200; 70700-271; 70771-1410; 70771-1471; 58032-2017; 0078-0468; 0078-0469; 31722-013; 43598-854; 69238-1488; 69452-159; 69539-023; 46708-410; 57664-768; 62332-324; 62756-568; 69539-021; 69539-073; 69539-199; 62332-412; 67877-550; 67877-553; 69097-391; 69097-560; 69539-022; 70771-1472; 65727-037; 0078-0655; 42806-371; 43598-851; 67877-554; 68462-495; 68462-496; 69097-392; 70710-1012; 62512-0078; 0078-0470; 0078-0654; 0078-0720; 31722-029; 43598-856; 46708-411; 46708-412; 69097-393; 69238-1486; 69539-303; 70710-1276; 72205-176; 14501-0049; 63278-1070; 65085-0063; 66022-0301; 0078-0656; 31722-031; 43598-855; 57664-769; 62332-325; 62756-569; 69539-075; 70710-1011; 72205-075; 72647-372; 74436-0323; 31722-012; 43598-853; 62332-326; 62332-411; 62756-570; 68462-494; 69097-570; 69238-1487; 69238-1702; 69238-1704; 70710-1013; 70771-1411; 70771-1473; 0591-3853; 72647-371; 0591-2961; 11722-040; 53104-7713; 59651-419; 0078-0727; 42806-372; 46708-324; 46708-325; 57664-770; 67877-549; 69539-074; 70700-270; 72205-076; 65015-738; 0078-0713; 31722-011; 42806-373; 45963-455; 46708-326; 62332-410; 67877-551; 69097-550; 69452-160; 70700-269; 70710-1275; 70710-1277; 70771-1409; 72647-373; 65372-1164
UNII V8G4MOF2V9
Synonyms Deferasirox | 4-(3,5-Bis-(2-hydroxyphenyl)-(1,2,4)-triazol-1-yl)benzoic acid | ICL 670A | ICL-670A | ICL670A | ICL-670 | ICL670 | ICL 670 | Exjade
Chemical Information
Molecular Formula C21H15N3O4
CAS Registry Number 201530-41-8
SMILES C1=CC=C(C(=C1)C2=NN(C(=N2)C3=CC=CC=C3O)C4=CC=C(C=C4)C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Spinal disorder15.02.04.0230.001859%Not Available
Decreased appetite08.01.09.028; 14.03.01.0050.048202%
Renal injury20.01.03.015; 12.01.05.0010.008550%Not Available
Inner ear disorder04.04.02.002--Not Available
Ulcer haemorrhage24.07.01.040; 08.03.06.0030.001859%Not Available
Blood disorder01.05.01.0040.010161%Not Available
Immunodeficiency10.03.02.0020.004337%Not Available
Bone marrow disorder01.05.01.0060.007063%Not Available
Disease progression08.01.03.0380.060717%
Disease recurrence08.01.03.0500.004337%Not Available
Drug intolerance08.06.01.0130.054645%Not Available
Hepatic lesion09.01.08.0050.001239%Not Available
Hepatobiliary disease09.01.08.003--Not Available
Pigmentation disorder23.05.03.001--Not Available
Venoocclusive disease24.03.02.0160.001239%Not Available
Metabolic encephalopathy17.13.01.001; 14.11.01.0130.002478%Not Available
Urinary tract pain20.02.03.0130.003346%
Renal impairment20.01.03.0100.065054%Not Available
Respiratory tract infection22.07.07.001; 11.01.08.017--Not Available
Poor quality sleep19.02.05.005; 17.15.04.0020.003965%Not Available
Middle ear effusion04.05.03.0010.001239%Not Available
Bowel movement irregularity07.02.03.0030.001239%Not Available
Hypophagia19.09.01.004; 14.03.01.006; 07.01.06.0100.003717%Not Available
Skin haemorrhage24.07.01.103; 23.06.07.0010.002726%Not Available
Osteonecrosis of jaw24.04.05.005; 15.02.04.010--
Chronic kidney disease20.01.03.0170.007435%
Bone marrow failure01.03.03.0050.009913%
Loose tooth07.09.05.0090.003965%Not Available
Iron overload14.13.03.002; 12.02.08.0050.027756%
Cytopenia01.03.03.0120.002478%Not Available
The 15th Page    First    Pre   15 16 17 18    Next   Last    Total 18 Pages