Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Dexmedetomidine
Drug ID BADD_D00629
Description An agonist of receptors, adrenergic alpha-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of dexmedetomidine.
Indications and Usage For sedation of initially intubated and mechanically ventilated patients during treatment in an intensive care setting, also used in pain relief; anxiety reduction and analgesia
Marketing Status approved; vet_approved
ATC Code N05CM18
DrugBank ID DB00633
KEGG ID D00514
MeSH ID D020927
PubChem ID 5311068
TTD Drug ID D0U3DU
NDC Product Code 55150-209; 81092-1180; 16729-432; 68083-527; 81092-1120; 67457-251; 70860-605; 66794-230; 66794-238; 62068-308; 16729-239; 71288-505; 66794-233; 71872-7150
UNII 67VB76HONO
Synonyms Dexmedetomidine | MPV-1440 | MPV 1440 | MPV1440 | Precedex | Dexmedetomidine Hydrochloride | Hydrochloride, Dexmedetomidine
Chemical Information
Molecular Formula C13H16N2
CAS Registry Number 113775-47-6
SMILES CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypovolaemia14.05.05.002--Not Available
Hypoxia22.02.02.0030.000131%
Illusion19.10.05.006--Not Available
Infection11.01.08.002--Not Available
Injection site extravasation12.07.03.002; 08.02.03.0020.000444%Not Available
Irritability19.04.02.013; 08.01.03.0110.000287%
Laryngeal pain22.12.03.010--
Laryngospasm22.04.02.0020.000196%
Lethargy08.01.01.008; 19.04.04.004; 17.02.04.0030.000131%
Leukocytosis01.02.01.002--
Light anaesthesia25.01.03.003--Not Available
Loss of consciousness17.02.04.0040.000653%Not Available
Malabsorption14.02.01.004; 07.17.01.0010.000131%
Metabolic acidosis14.01.01.003--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Myocardial ischaemia24.04.04.010; 02.02.02.0080.000392%Not Available
Nausea07.01.07.001--
Nephropathy20.05.03.001--Not Available
Neuralgia17.02.07.005--
Neuritis17.09.03.001--Not Available
Neuroleptic malignant syndrome15.05.04.015; 12.03.01.003; 08.05.01.005; 17.05.02.0030.000196%Not Available
Neuropathy peripheral17.09.03.003--Not Available
Nodal rhythm02.03.03.0210.000196%Not Available
Oedema peripheral14.05.06.011; 08.01.07.007; 02.05.04.007--
Oliguria20.01.03.004--Not Available
Pain08.01.08.004--
Photopsia17.17.01.006; 06.02.06.004--
Pleural effusion22.05.02.002--
Pneumonia22.07.01.003; 11.01.09.003--Not Available
Pneumothorax22.05.02.003--
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