Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Emedastine difumarate
Drug ID BADD_D00764
Description Emedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Indications and Usage For the temporary relief of the signs and symptoms of allergic conjunctivitis.
Marketing Status approved
ATC Code S01GX06
DrugBank ID DB01084
KEGG ID D02249
MeSH ID C043345
PubChem ID 5282485
TTD Drug ID D02XJI
NDC Product Code 12863-100
UNII 42MB94QOSM
Synonyms emedastine | emedastine difumarate | 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)benzimidazole difumarate | KB 2413 | KG 2413 | KG-2413 | KB-2413 | Emadine
Chemical Information
Molecular Formula C25H34N4O9
CAS Registry Number 87233-62-3
SMILES CCOCCN1C2=CC=CC=C2N=C1N3CCCN(CC3)C.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Asthenia08.01.01.001--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Corneal infiltrates06.08.01.002--Not Available
Dermatitis23.03.04.002--Not Available
Discomfort08.01.08.003--Not Available
Dry eye06.08.02.001--
Dysgeusia17.02.07.003; 07.14.03.001--
Headache17.14.01.001--
Hyperaemia24.03.02.002--Not Available
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Pain08.01.08.004--
Pruritus23.03.12.001--
Rhinitis22.07.03.006; 11.01.13.004--
Sinusitis22.07.03.007; 11.01.13.005--
Vision blurred06.02.06.007; 17.17.01.010--
Vital dye staining cornea present13.07.04.010--Not Available
Sensation of foreign body08.01.09.002--Not Available
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