Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Ethosuximide
Drug ID BADD_D00846
Description An anticonvulsant especially useful in the treatment of absence seizures unaccompanied by other types of seizures.
Indications and Usage For the treatment of petit mal epilepsy.
Marketing Status approved
ATC Code N03AD01
DrugBank ID DB00593
KEGG ID D00539
MeSH ID D005013
PubChem ID 3291
TTD Drug ID D0Q4XQ
NDC Product Code 65655-0001; 0071-2418; 61748-025; 49452-2803; 0121-0670; 17349-0006; 59762-2250; 63629-8005; 59762-2350; 23155-532; 0071-0237; 42806-708; 64380-878; 69452-152; 11014-0047; 51927-3436; 42806-711; 10888-8169
UNII 5SEH9X1D1D
Synonyms Ethosuximide | Ethosuccimid | Ethylmethylsuccimide | Ethymal | Zarontin | Petnidan | Pyknolepsinum | Suksilep | Suxilep | Emeside | Etosuximida Faes | Faes, Etosuximida
Chemical Information
Molecular Formula C7H11NO2
CAS Registry Number 77-67-8
SMILES CCC1(CC(=O)NC1=O)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Pancytopenia01.03.03.003--Not Available
Paranoia19.05.01.005--Not Available
Petit mal epilepsy17.12.04.0010.006339%Not Available
Pruritus23.03.12.0010.004226%
Psychomotor hyperactivity19.11.02.003; 17.01.02.011--Not Available
Pyrexia08.05.02.0030.016903%
Rash23.03.13.0010.039300%Not Available
Rash erythematous23.03.13.029--Not Available
Rash pruritic23.03.13.0300.004226%Not Available
Raynaud's phenomenon24.04.03.0030.006339%Not Available
Retching07.01.07.0020.009297%Not Available
Sedation17.02.04.0050.009297%Not Available
Seizure17.12.03.0010.047329%
Skin disorder23.03.03.007--Not Available
Sleep disorder19.02.04.001--Not Available
Sleep terror19.02.03.008; 17.15.02.006--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Status epilepticus17.12.03.0050.010564%Not Available
Stevens-Johnson syndrome12.03.01.014; 11.07.01.005; 10.01.01.045; 23.03.01.0070.004226%
Suicidal ideation19.12.01.0030.004226%
Suicide attempt19.12.01.0040.006339%
Swollen tongue23.04.01.014; 10.01.05.015; 07.14.02.003--Not Available
Systemic lupus erythematosus10.04.03.004; 23.03.02.006; 15.06.02.0030.004226%Not Available
Thrombocytopenia01.08.01.0020.004226%Not Available
Tongue disorder07.14.01.002--Not Available
Tongue oedema23.04.01.009; 10.01.05.008; 07.14.02.007--Not Available
Toxic epidermal necrolysis23.03.01.008; 12.03.01.015; 11.07.01.006; 10.01.01.0060.004226%
Tremor17.01.06.0020.004226%
Unresponsive to stimuli17.02.05.0310.004226%Not Available
Urethral disorder20.07.01.002--Not Available
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