Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Status epilepticus
ADR ID BADD_A04150
ADR Hierarchy
17      Nervous system disorders
17.12      Seizures (incl subtypes)
17.12.03      Seizures and seizure disorders NEC
17.12.03.005      Status epilepticus
Description A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30) [MeSH]
MedDRA Code 10041962
MeSH ID D013226
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Grand mal status, epileptic | Status epilepticus | Status epilepticus grand mal | Nonconvulsive status epilepticus | Complex partial status epilepticus | Convulsive status epilepticus | Tonic status epilepticus | Hemiclonic state | Status Epilepticus | Status Epilepticus, Generalized | Generalized Status Epilepticus | Grand Mal Status Epilepticus | Status Epilepticus, Grand Mal | Status Epilepticus, Generalized Convulsive | Generalized Convulsive Status Epilepticus | Non-Convulsive Status Epilepticus | Non Convulsive Status Epilepticus | Status Epilepticus, Non-Convulsive | Status Epilepticus, Non Convulsive | Status Epilepticus, Subclinical | Subclinical Status Epilepticus | Status Epilepticus, Electrographic | Electrographic Status Epilepticus | Simple Partial Status Epilepticus | Status Epilepticus, Simple Partial | Complex Partial Status Epilepticus | Status Epilepticus, Complex Partial | Petit Mal Status | Status, Petit Mal | Absence Status | Status, Absence
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00032Acetylcysteine0.000149%
BADD_D00039Acyclovir0.000071%
BADD_D00076Allopurinol--
BADD_D00085Alprazolam0.000136%
BADD_D00115Amiodarone0.000135%
BADD_D00143Anidulafungin0.000150%
BADD_D00165Aripiprazole0.000317%
BADD_D00180Atomoxetine0.000232%
BADD_D00209Baclofen0.001288%
BADD_D00297Brivaracetam0.000311%
BADD_D00305Bromocriptine mesylate--
BADD_D00312Bupropion0.001692%
BADD_D00356Carbamazepine0.003720%
BADD_D00370Carisoprodol0.000126%
BADD_D00371Carmustine0.000112%
BADD_D00386Cefepime0.000933%
BADD_D00387Cefepime hydrochloride--
BADD_D00399Ceftazidime0.000243%
BADD_D00405Ceftriaxone0.033424%
BADD_D00471Ciprofloxacin--
BADD_D00480Clarithromycin0.000335%
BADD_D00488Clobazam0.001006%
BADD_D00501Clonazepam0.000059%
BADD_D00511Clozapine--
BADD_D00545Cyclobenzaprine0.000016%
BADD_D00551Cyclosporine0.000276%
BADD_D00648Diazepam0.000302%
BADD_D00668Digoxin0.000211%
BADD_D00686Diphenhydramine0.001477%
BADD_D00706Donepezil0.000070%
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