| Pharmaceutical Information |
| Drug Name |
Etidronate disodium |
| Drug ID |
BADD_D00848 |
| Description |
Etidronic acid is a first generation bisphosphonate similar to [clodronic acid] and [tiludronic acid].[A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.[A1923] Etidronate’s use has decreased over the years in favor of the third generation, nitrogen containing bisphosphonate [zoledronic acid], [ibandronic acid], [minodronic acid], and [risedronic acid].[A203111]
Etidronic acid was granted FDA approval on 1 September 1977.[L13901] |
| Indications and Usage |
Etidronate is indicated to treat Paget's disease of bone, as well as the treatment and prevention of heterotropic ossification after total hip replacement of spinal cord injury.[L13901] |
| Marketing Status |
approved |
| ATC Code |
M05BA01 |
| DrugBank ID |
DB01077
|
| KEGG ID |
D00314
|
| MeSH ID |
D012968
|
| PubChem ID |
23894
|
| TTD Drug ID |
D00XUN
|
| NDC Product Code |
Not Available |
| UNII |
M16PXG993G
|
| Synonyms |
Etidronic Acid | (1-hydroxyethylene)diphosphonic acid | Hydroxyethylidene Diphosphonic Acid | Diphosphonic Acid, Hydroxyethylidene | Etidronate | 1-Hydroxyethane-1,1-Diphosphonate | 1 Hydroxyethane 1,1 Diphosphonate | 1-Hydroxyethylidene-1,1-Bisphosphonate | 1 Hydroxyethylidene 1,1 Bisphosphonate | EHDP | 1,1-hydroxyethylenediphosphonate | 1,1 hydroxyethylenediphosphonate | HEDP | Hydroxyethanediphosphonate | Ethanehydroxyphosphate | Ethanehydroxydiphosphonate | Etidronate Disodium | Phosphonic acid, (1-hydroxyethylidene)bis-, disodium salt | Sodium Etidronate | Etidronate, Sodium | Disodium 1-Hydroxyethylene Diphosphonate | 1-Hydroxyethylene Diphosphonate, Disodium | Diphosphonate, Disodium 1-Hydroxyethylene | Disodium 1 Hydroxyethylene Diphosphonate | Disodium Etidronate | Etidronate, Disodium | HEDSPA | Dicalcium Etidronate | Etidronate, Dicalcium | Dicalcium EHDP | EHDP, Dicalcium | Xidifon | Xydiphone | Xidiphon | Didronel | Etidronate, Tetrapotassium Salt | Salt Etidronate, Tetrapotassium | Tetrapotassium Salt Etidronate | (1-hydroxyethylene)diphosphonic acid, Tetrapotassium Salt |
|
| Chemical Information |
| Molecular Formula |
C2H6Na2O7P2 |
| CAS Registry Number |
7414-83-7 |
| SMILES |
CC(O)(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+] |
| Chemical Structure |
|
|
| ADRs Induced by Drug |
|
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|
|
