| Drug Name |
Hydroxychloroquine sulfate |
| Drug ID |
BADD_D01104 |
| Description |
Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine].[L8072] It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus.[L8072] Hydroxychloroquine is also used for the prophylaxis of malaria in regions where chloroquine resistance is unlikely.[L8072] It was developed during World War II as a derivative of [quinacrine] with less severe side effects.[A183092] Chloroquine and hydroxychloroquine are both being investigated for the treatment of SARS-CoV-2.[A192132]
**The FDA emergency use authorization for hydroxychloroquine and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020.[L14312]**
Hydroxychloroquine was granted FDA approval on 18 April 1955.[L8072]
A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546] |
| Indications and Usage |
Hydroxychloroquine is indicated for the prophylaxis of malaria where chloroquine resistance is not reported, treatment of uncomplicated malaria (caused by _P. falciparum_, _P. malariae_, _P. ovale_, or _P. vivax_), chronic discoid lupus erythematosus, systemic lupus erythematosus, acute rheumatoid arthritis, and chronic rheumatoid arthritis.[L8072] |
| Marketing Status |
approved |
| ATC Code |
P01BA02 |
| DrugBank ID |
DB01611
|
| KEGG ID |
D02114
|
| MeSH ID |
D006886
|
| PubChem ID |
12947
|
| TTD Drug ID |
D0OJ4L
|
| NDC Product Code |
51927-0279; 67835-0027; 16729-562; 43353-051; 50090-6280; 68071-2912; 68084-269; 71335-1771; 0615-8401; 0093-2401; 50268-412; 55154-3567; 71335-1523; 71610-506; 49452-3625; 70966-0022; 72640-020; 73309-106; 16571-687; 16714-110; 59212-562; 68382-096; 71610-473; 63739-777; 65841-633; 68071-4648; 71610-701; 0904-7046; 50095-002; 82231-108; 43598-133; 60219-1544; 71335-1949; 16729-561; 50090-5573; 57664-761; 67296-1780; 70954-172; 71205-448; 0781-5994; 57451-0198; 16729-485; 16729-563; 53808-1112; 69238-1544; 71335-0897; 57451-1118; 71796-031; 45542-1161; 42385-927; 43598-131; 59746-780; 67296-1781; 12780-2771; 65841-103; 68108-0336; 43598-721; 55154-2074; 68788-7747; 70954-171; 0615-8459; 76385-144; 82009-045; 67680-003; 71052-659; 73377-041; 16571-112; 43598-132 |
| UNII |
8Q2869CNVH
|
| Synonyms |
Hydroxychloroquine | Oxychlorochin | Oxychloroquine | Hydroxychlorochin | Plaquenil | Hydroxychloroquine Sulfate | Hydroxychloroquine Sulfate (1:1) Salt |
