Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Iodixanol
Drug ID BADD_D01178
Description Iodixanol is a nonionic hydrophilic compound commonly used as a contrast agent during coronary angiography, particularly in individuals with renal dysfunction, as it is believed to be less toxic to the kidneys than most other intravascular contrast agents.
Indications and Usage Iodixanol is a contrast agent during coronary angiography.
Marketing Status approved
ATC Code V08AB09
DrugBank ID DB01249
KEGG ID D01474
MeSH ID C044834
PubChem ID 3724
TTD Drug ID D0Y4YG
NDC Product Code 71806-222; 65219-381; 0407-2223; 65219-383; 0407-2222; 57884-0029
UNII HW8W27HTXX
Synonyms iodixanol | Visipaque | Visipaque Unique Softpac | iodixanol-320 | contrast media 2-5410-3
Chemical Information
Molecular Formula C35H44I6N6O15
CAS Registry Number 92339-11-2
SMILES CC(=O)N(CC(CN(C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I)C(=O)C)O)C2=C(C(= C(C(=C2I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Conjunctivitis11.01.06.012; 06.04.01.002--
Contrast media reaction12.02.05.029; 10.01.01.0110.118082%Not Available
Cough22.02.03.0010.185659%
Cyanosis23.06.04.005; 02.11.04.004; 24.03.01.007; 22.02.02.0070.072557%
Deafness04.02.01.001--Not Available
Delirium19.13.02.0010.010670%
Depressed level of consciousness17.02.04.0020.014227%
Dermatitis23.03.04.0020.010670%Not Available
Dermatitis allergic23.03.04.003; 10.01.03.0140.067577%Not Available
Dermatitis bullous23.03.01.0020.017783%
Diarrhoea07.02.01.001--
Diplopia17.17.01.005; 06.02.06.0020.007113%Not Available
Discomfort08.01.08.0030.017783%Not Available
Disorientation19.13.01.002; 17.02.05.0150.007113%Not Available
Disseminated intravascular coagulation24.01.01.010; 01.01.02.002--
Dizziness17.02.05.003; 02.11.04.006; 24.06.02.0070.109546%
Drug eruption23.03.05.001; 10.01.01.005; 08.01.06.0150.014227%Not Available
Dry mouth07.06.01.0020.017783%
Dry skin23.03.03.001--
Dysgeusia17.02.07.003; 07.14.03.001--
Dyskinesia17.01.02.006--
Dyspepsia07.01.02.001--
Dysphagia07.01.06.0030.028454%
Dysphonia22.12.03.006; 19.19.03.002; 17.02.08.0040.053350%
Dysphoria19.04.02.0040.024897%Not Available
Dyspnoea02.11.05.003; 22.02.01.0040.468061%
Dystonia17.01.03.0010.014227%Not Available
Ear pain04.03.01.003--
Encephalopathy17.13.02.0010.010670%
Eosinophilia01.02.04.0010.032010%
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ADReCS-Target
Drug Name ADR Term Target
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