Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Ioxilan
Drug ID BADD_D01189
Description Ioxilan is a tri-iodinated diagnostic contrast agent. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs.
Indications and Usage When administered intra-arterially, Ioxilan is indicated for the following diagnostic tests: cerebral arteriography (300 mgI/mL), coronary arteriography and left ventriculography (350 mgI/mL), visceral angiography(350 mgI/mL), aortography(350 mgI/mL), and peripheral arteriography(350 mgI/mL). When administered intravenously, Ioxilan is indicated for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body (300 and 350 mgI/mL).
Marketing Status approved
ATC Code V08AB12
DrugBank ID DB09135
KEGG ID D02161
MeSH ID C055357
PubChem ID 3743
TTD Drug ID D02BLO
NDC Product Code Not Available
UNII A4YJ7J11TG
Synonyms ioxilan | 5-(N-2,3-dihydroxypropylacetamido)-2,4,6-triiodo-N-(2-hydroxyethyl)-N'-(2,3-dihydroxypropyl)isophthalamide | Oxilan
Chemical Information
Molecular Formula C18H24I3N3O8
CAS Registry Number 107793-72-6
SMILES CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCCO)I
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Hypotension24.06.03.002--
Hypotonia17.05.02.002; 15.05.04.008--Not Available
Ileus07.13.01.001--
Infection11.01.08.002--Not Available
Loss of consciousness17.02.04.004--Not Available
Nausea07.01.07.001--
Nystagmus17.02.02.006; 06.05.02.006--
Oedema14.05.06.010; 08.01.07.006--Not Available
Oedema peripheral08.01.07.007; 14.05.06.011; 02.05.04.007--
Pain08.01.08.004--
Paraesthesia17.02.06.005; 23.03.03.094--
Pharyngitis22.07.03.004; 11.01.13.003; 07.05.07.004--
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Renal failure20.01.03.005--Not Available
Rhinitis11.01.13.004; 22.07.03.006--
Shock24.06.02.002--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Ventricular extrasystoles02.03.04.007--Not Available
Vertigo17.02.12.002; 04.04.01.003--
Vomiting07.01.07.003--
Vasodilation procedure25.03.01.001--Not Available
Muscle relaxant therapy25.16.01.001--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
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