Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Levomilnacipran hydrochloride
Drug ID BADD_D01280
Description Levomilnacipran is a selective serotonin and norepinephrine reuptake inhibitor. Chemically, levomilnacipran is the 1S,2R-enantiomer of milnacipran. FDA approved on July 25, 2013.
Indications and Usage Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor and is indicated for the treatment of major depressive disorder (MDD).
Marketing Status approved; investigational
ATC Code N06AX28
DrugBank ID DB08918
KEGG ID D10133
MeSH ID D000078862
PubChem ID 6917778
TTD Drug ID D02XOK
NDC Product Code 50370-0043; 0456-2221; 53069-1090; 0456-2202; 0456-2212; 0456-2220; 0456-2200; 0456-2281; 69766-018; 0456-2280; 0456-2213; 0456-2241; 53069-1100; 51604-1183; 0456-2240
UNII 371U2ZK31U
Synonyms Levomilnacipran | Fetzima | Levomilnacipran Hydrochloride
Chemical Information
Molecular Formula C15H23ClN2O
CAS Registry Number 101152-94-7
SMILES CCN(CC)C(=O)C1(CC1CN)C2=CC=CC=C2.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Aggression19.05.01.001--Not Available
Agitation19.06.02.001; 17.02.05.012--
Anger19.04.02.001--Not Available
Angina pectoris24.04.04.002; 02.02.02.002--
Angle closure glaucoma06.03.01.001--Not Available
Blood cholesterol increased13.12.01.002--
Blood pressure diastolic increased13.14.03.004--Not Available
Blood pressure increased13.14.03.005--Not Available
Blood pressure systolic increased13.14.03.006--Not Available
Bruxism19.11.03.001; 07.01.06.008--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Conjunctival haemorrhage24.07.05.001; 06.07.01.001--Not Available
Constipation07.02.02.001--
Dermatitis23.03.04.002--Not Available
Dizziness24.06.02.007; 17.02.05.003; 02.11.04.006--
Dizziness postural17.02.05.004; 02.11.04.008; 24.06.02.008--Not Available
Dry eye06.08.02.001--
Dry skin23.03.03.001--
Ejaculation delayed21.03.01.001--Not Available
Ejaculation disorder21.03.01.002--
Ejaculation failure21.03.01.003--Not Available
Epididymitis11.01.19.005; 21.09.02.001--Not Available
Extrapyramidal disorder17.01.02.007--
Eye disorder06.08.03.001--Not Available
Flatulence07.01.04.002--
Gastrointestinal disorder07.11.01.001--Not Available
Gastrointestinal pain07.01.05.005--
Haematuria21.10.01.018; 24.07.01.047; 20.02.01.006--
Haemorrhagic disorder24.07.01.021; 01.01.03.004--Not Available
The 1th Page    1 2 3 4    Next   Last    Total 4 Pages