| Pharmaceutical Information |
| Drug Name |
Lodoxamide |
| Drug ID |
BADD_D01307 |
| Description |
Lodoxamide is a mast-cell stabilizer for topical administration into the eye. Mast-cell stabilizers, first one approved being cromolyn sodium, are used in treatment of ocular hypersensitivity reactions such as vernal conjunctivitis. These conditions often require treatment with anti-inflammatory medications such as ophthalmic NSAIDs or topical steroids which may cause systemic or toxic effects long-term. Although less effective than topical steroids at decreasing inflammation, mast-cell stabilizers offer another treatment option and exhibit minimal adverse effects. Lodoxamide is marketed under the brand name Alomide by Alcon. |
| Indications and Usage |
Indicated in the treatment of the ocular disorders referred to by the terms vernal keratoconjunctivitis, vernal conjunctivitis, and vernal keratitis. |
| Marketing Status |
approved |
| ATC Code |
S01GX05 |
| DrugBank ID |
DB06794
|
| KEGG ID |
D08139
|
| MeSH ID |
C021702
|
| PubChem ID |
44564
|
| TTD Drug ID |
D0OG3K
|
| NDC Product Code |
58567-102 |
| UNII |
SPU695OD73
|
| Synonyms |
lodoxamide ethyl | diethyl N,N'-(2-chloro-5-cyano-m-phenylene)dioxamate | U-42,718 | lodoxamide |
|
| Chemical Information |
| Molecular Formula |
C11H6ClN3O6 |
| CAS Registry Number |
53882-12-5 |
| SMILES |
C1=C(C=C(C(=C1NC(=O)C(=O)O)Cl)NC(=O)C(=O)O)C#N |
| Chemical Structure |
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| ADRs Induced by Drug |
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