Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methylprednisolone sodium succinate
Drug ID BADD_D01436
Description A water-soluble ester of methylprednisolone used for cardiac, allergic, and hypoxic emergencies.
Indications and Usage Not Available
Marketing Status approved
ATC Code Not Available
DrugBank ID DB14644
KEGG ID D00751
MeSH ID D008776
PubChem ID 23680530
TTD Drug ID Not Available
NDC Product Code 0404-9957; 71872-7061; 0009-0003; 0009-0047; 0143-9754; 43598-129; 0009-0698; 52584-039; 52584-047; 0009-0850; 55150-263; 55154-3940; 55154-3941; 63323-255; 43598-128; 70518-2023; 0143-9850; 63323-265; 0404-9958; 71872-7232; 55150-262; 55150-265; 70518-3684; 0009-0039; 0143-9753; 71872-7085; 0143-9851; 55154-3939; 55154-3944; 43598-127; 50090-0271; 63323-258; 0009-0018; 43598-130; 0009-0758; 55150-264
UNII LEC9GKY20K
Synonyms Methylprednisolone Hemisuccinate | Hemisuccinate, Methylprednisolone | Methylprednisolone Succinate | Succinate, Methylprednisolone | Urbason-Soluble | UrbasonSoluble | Solu-Medrol | Solumedrol | A-MethaPred | Methylprednisolone Sodium Succinate | Sodium Succinate, Methylprednisolone | Methylprednisolone Hemisuccinate Monosodium Salt | 6 alpha-Methylprednisolone Sodium Hemisuccinate | Methylprednisolone Sodium Hemisuccinate | Sodium Hemisuccinate, Methylprednisolone
Chemical Information
Molecular Formula C26H33NaO8
CAS Registry Number 2375-03-3
SMILES CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)COC(=O)CCC(=O)[O-])O.[Na+]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Neuritis17.09.03.001--Not Available
Neuropathic arthropathy15.01.04.008; 14.07.04.011; 05.07.04.011; 17.09.03.008--Not Available
Neuropathy peripheral17.09.03.003--Not Available
Nitrogen balance negative13.13.01.010--Not Available
Oedema14.05.06.010; 08.01.07.006--Not Available
Osteonecrosis24.04.05.004; 15.02.04.007--
Osteoporosis15.02.03.002; 14.04.04.002--
Pancreatitis07.18.01.001--
Papilloedema17.07.02.004; 06.09.02.002; 24.03.07.001--
Paraesthesia23.03.03.094; 17.02.06.005--
Pathological fracture16.32.03.007; 15.08.02.008; 12.04.02.006--Not Available
Peptic ulcer07.04.07.001--Not Available
Personality change19.05.01.006; 17.02.05.019--
Petechiae24.07.06.004; 23.06.01.003; 01.01.03.002--Not Available
Pulmonary oedema22.01.03.003; 02.05.02.003--
Rash23.03.13.001--Not Available
Secondary adrenocortical insufficiency05.03.04.012; 14.11.01.014--Not Available
Seizure17.12.03.001--
Skin atrophy23.01.05.001--
Skin hyperpigmentation23.05.01.003--
Skin hypopigmentation23.05.02.003--
Skin striae23.01.05.002--Not Available
Small intestinal perforation07.04.06.006--
Sodium retention14.05.04.003--Not Available
Spermatozoa progressive motility abnormal13.20.04.011--Not Available
Spinal compression fracture15.08.05.004; 14.04.04.003; 12.04.04.001--Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Tendon rupture12.01.07.003; 15.07.01.008--Not Available
Thrombophlebitis24.01.02.001--Not Available
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