Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Pentazocine lactate
Drug ID BADD_D01720
Description The first mixed agonist-antagonist analgesic to be marketed. It is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Indications and Usage For the relief of moderate to severe pain.
Marketing Status approved; vet_approved
ATC Code N02AD01
DrugBank ID DB00652
KEGG ID D02111
MeSH ID D010423
PubChem ID 656697
TTD Drug ID D0W6DG
NDC Product Code 48087-0007
UNII 1P2XIB510O
Synonyms Pentazocine | Lexir | Pentazocine Lactate | Lactate, Pentazocine | Talwin | Fortral | Pentazocine Hydrochloride | Hydrochloride, Pentazocine
Chemical Information
Molecular Formula C22H33NO4
CAS Registry Number 17146-95-1
SMILES CC1C2CC3=C(C1(CCN2CC=C(C)C)C)C=C(C=C3)O.CC(C(=O)O)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nightmare19.02.03.003--Not Available
Nystagmus17.02.02.006; 06.05.02.006--
Oedema14.05.06.010; 08.01.07.006--Not Available
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
Palpitations02.11.04.012--
Paraesthesia23.03.03.094; 17.02.06.005--
Paralysis17.01.04.004--Not Available
Pruritus23.03.12.001--
Rash23.03.13.001--Not Available
Rash erythematous23.03.13.029--Not Available
Rash maculo-papular23.03.13.004--
Respiratory depression22.02.01.010; 17.02.05.047--Not Available
Sedation17.02.04.005--Not Available
Shock24.06.02.002--Not Available
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.003--Not Available
Skin ulcer24.04.03.007; 23.07.03.003--
Somnolence17.02.04.006; 19.02.05.003--
Speech disorder22.12.03.027; 19.19.02.002; 17.02.08.003--Not Available
Stridor22.04.02.003--
Stupor19.02.05.004; 17.02.04.007--Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.008--
Tachycardia02.03.02.007--Not Available
Tachypnoea22.02.01.014--Not Available
Tinnitus17.04.07.004; 04.04.01.002--
Tongue oedema23.04.01.009; 10.01.05.008; 07.14.02.007--Not Available
Toxic epidermal necrolysis10.01.01.006; 23.03.01.008; 12.03.01.015; 11.07.01.006--
Tremor17.01.06.002--
Urinary retention20.02.02.011--
Vascular headache24.03.05.007; 17.14.01.005--Not Available
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