Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Praziquantel
Drug ID BADD_D01826
Description An anthelmintic used in most schistosome and many cestode infestations.
Indications and Usage For the treatment of infections due to all species of schistosoma.
Marketing Status approved; investigational; vet_approved
ATC Code P02BA01
DrugBank ID DB01058
KEGG ID D00471
MeSH ID D011223
PubChem ID 4891
TTD Drug ID D0L9ZR
NDC Product Code 53104-7567; 72643-005; 86055-0003; 13371-321; 71052-203; 12527-2521; 14639-0022; 62991-2053; 49169-1027; 49452-5976; 49884-231; 50419-747; 38779-0090; 10745-0422; 52562-022; 69011-0001
UNII 6490C9U457
Synonyms Praziquantel | Prasiquantel | Praziquantel, (+-)-Isomer | Praziquantel, (R)-Isomer | Praziquantel, (S)-Isomer | Drontsit | Traziquantel | Biltricide | Cesol | Cysticide | Cisticid | Droncit | EMBAY 8440 | Pyquiton
Chemical Information
Molecular Formula C19H24N2O2
CAS Registry Number 55268-74-1
SMILES C1CCC(CC1)C(=O)N2CC3C4=CC=CC=C4CCN3C(=O)C2
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Oesophageal varices haemorrhage24.07.02.022; 09.01.06.004; 07.12.01.0030.001691%
Photosensitivity reaction23.03.09.0030.001691%
Polyserositis08.01.05.003--Not Available
Portal hypertension24.08.06.001; 09.01.06.0060.002536%
Portal vein thrombosis09.01.06.007; 24.01.03.0030.001691%
Pruritus23.03.12.0010.004564%
Pyrexia08.05.02.0030.005072%
Rash23.03.13.0010.005410%Not Available
Seizure17.12.03.001--
Skin disorder23.03.03.007--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Splenomegaly01.09.02.0010.001691%Not Available
Syncope02.11.04.015; 24.06.02.012; 17.02.04.0080.001691%
Urticaria23.04.02.001; 10.01.06.0010.003381%
Ventricular fibrillation02.03.04.008--
Vertigo04.04.01.003; 17.02.12.002--
Vomiting07.01.07.0030.002536%
Acute generalised exanthematous pustulosis11.07.01.018; 10.01.01.034; 23.03.10.002; 12.03.01.0050.001691%Not Available
General physical health deterioration08.01.03.0180.001691%Not Available
Musculoskeletal discomfort15.03.04.001--Not Available
Cardiac disorder02.11.01.003--Not Available
Decreased appetite14.03.01.005; 08.01.09.028--
Ill-defined disorder08.01.03.049--Not Available
Portal fibrosis09.01.04.008; 24.08.06.0040.001691%Not Available
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