Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Prednisolone acetate
Drug ID BADD_D01832
Description Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]
Indications and Usage Prednisolone acetate is indicated as an anti-inflammatory or immunosuppressive agent for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, or infectious conditions.[L9449] Prednisolone acetate is also indicated in organ transplant patients, as well as endocrine or neoplastic conditions.[L9449]
Marketing Status approved; vet_approved
ATC Code Not Available
DrugBank ID DB15566
KEGG ID D00980
MeSH ID C009935
PubChem ID 5834
TTD Drug ID Not Available
NDC Product Code 38779-0152; 62991-1692; 50090-0559; 50090-1912; 50090-5275; 61314-637; 49452-5990; 82298-107; 11980-180; 60758-119; 60722-3006; 82298-108; 52128-150; 11980-174; 46439-8761; 51552-0027; 64958-0048; 76420-204; 22552-0044; 68071-2222
UNII 8B2807733D
Synonyms prednisolone acetate | prednisolone 21-acetate | pred forte | Scherisolone-Kristall suspension
Chemical Information
Molecular Formula C23H30O6
CAS Registry Number 52-21-1
SMILES CC(=O)OCC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)C=CC34C)O)C)O
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Vertigo17.02.12.002; 04.04.01.003--
Vision blurred17.17.01.010; 06.02.06.0070.086568%
Visual acuity reduced06.02.10.012; 17.17.01.0110.019213%
Visual impairment06.02.10.0130.045119%Not Available
Vitreous floaters06.09.01.0050.004749%
Weight increased13.15.01.006--
Hypoacusis04.02.01.0060.008419%
Oesophagitis ulcerative07.04.05.003--Not Available
Foreign body sensation in eyes06.01.01.0060.029360%Not Available
Acute coronary syndrome24.04.04.011; 02.02.02.015--Not Available
Conjunctival hyperaemia06.04.01.0040.004318%Not Available
Eyelid margin crusting23.03.03.029; 06.04.04.0050.007340%Not Available
Ocular discomfort06.08.03.0080.014680%Not Available
Nerve injury17.02.10.007; 12.01.12.002--Not Available
Growth retardation15.03.05.016; 14.03.02.031; 05.03.02.007--
Anterior chamber cell06.04.10.0010.002159%Not Available
Affect lability19.04.01.001--Not Available
Corneal thinning06.06.03.0090.002159%Not Available
Corneal neovascularisation24.03.07.009; 06.07.01.0030.004749%Not Available
Haemorrhage24.07.01.002--Not Available
Muscle mass15.05.03.018--Not Available
Cystoid macular oedema06.04.06.010; 12.02.02.0050.004318%Not Available
Hepatic enzyme increased13.03.04.028--Not Available
Skin test negative13.06.04.002--Not Available
Embolism24.01.01.009--
Lipid metabolism disorder14.08.04.003--Not Available
Ill-defined disorder08.01.03.049--Not Available
Ulcerative keratitis10.02.01.021; 06.04.02.0040.002159%
Treatment failure08.06.01.0170.689951%Not Available
Macular fibrosis06.09.03.0140.004318%Not Available
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