ADReCS

Pharmaceutical Information

Drug Name	Prednisone
Drug ID	BADD_D01834
Description	A synthetic anti-inflammatory glucocorticoid derived from [cortisone].[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Indications and Usage	Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.[L10502]
Marketing Status	approved; vet_approved
ATC Code	A07EA03; H02AB07
DrugBank ID	DB00635
KEGG ID	D00473
MeSH ID	D011241
PubChem ID	5865
TTD Drug ID	D0IL7L
NDC Product Code	80425-0068; 82982-041; 0591-5052; 42291-727; 42708-105; 43063-911; 50090-0439; 50090-3361; 51655-242; 53002-0610; 55154-4950; 58118-0173; 59746-175; 60219-1707; 61919-321; 62135-471; 63187-066; 63629-2255; 63629-2263; 0378-0642; 64380-949; 67296-0138; 67296-1194; 67296-1755; 68071-2304; 68071-5242; 70518-0632; 70518-2115; 70518-2138; 71205-729; 71205-755; 71205-818; 0054-4741; 71335-1926; 0591-5443; 71335-2153; 0603-5336; 76420-068; 80425-0069; 82982-042; 10135-777; 10135-779; 50090-3137; 51655-493; 51655-763; 51655-765; 51655-779; 55154-4938; 59746-171; 60760-932; 63187-807; 63629-2254; 63629-2434; 64380-835; 66267-173; 66267-860; 67296-1444; 68071-2661; 68071-4691; 68071-5195; 68788-7372; 68788-7692; 68788-8166; 68788-9551; 70518-2675; 70518-2704; 70518-3540; 70934-880; 70954-060; 71205-741; 71335-2088; 0054-8739; 72162-1169; 72189-275; 0615-8438; 80425-0105; 64958-0002; 43063-968; 50090-6225; 51655-410; 51655-988; 53002-3090; 54348-506; 55154-4946; 55289-330; 55700-208; 60219-1705; 61919-235; 61919-365; 63629-7917; 67296-0140; 0054-0019; 68788-8212; 70954-061; 71205-089; 71335-1780; 71335-2149; 0054-8724; 0054-8740; 0054-9828; 72162-1170; 0615-8307; 0615-8441; 59651-489; 60760-002; 63629-2256; 64380-782; 67296-1183; 0054-0018; 70518-1553; 70518-2916; 70934-095; 70954-057; 71205-460; 71205-797; 71335-2122; 71335-2134; 0603-5337; 71610-721; 0054-9818; 0615-8306; 72189-489; 0615-8439; 80425-0106; 0904-6923; 13672-033; 10135-778; 43063-703; 45865-670; 53002-3252; 59746-172; 60687-145; 60760-255; 60760-790; 61919-108; 63187-085; 63629-2258; 63629-2435; 0378-0641; 68071-2209; 68071-2578; 68071-3143; 68788-6440; 68788-7752; 68788-8267; 70954-059; 71205-537; 71335-1524; 71335-1628; 71335-1736; 71335-1737; 71335-2051; 0603-5335; 0603-5339; 0615-8440; 75987-021; 75987-022; 0591-5442; 13672-032; 42708-115; 50090-3336; 51655-355; 51655-416; 51655-935; 51655-972; 59651-487; 60219-1708; 62135-470; 63187-300; 63187-997; 63629-2260; 63629-2262; 68071-1779; 68788-8116; 0527-2934; 70518-0305; 70518-0306; 70518-1120; 70882-117; 0054-4742; 71335-1516; 71335-1525; 0603-5338; 76420-067; 13672-031; 51552-0028; 10135-774; 42708-136; 50090-6123; 50090-6259; 51655-068; 51655-359; 51655-701; 53002-3091; 53002-3520; 59651-488; 60687-122; 63187-243; 63629-1579; 63629-2261; 0378-0640; 64380-784; 64380-785; 67296-0247; 67296-1065; 67296-1455; 67296-1457; 68071-2696; 68071-5196; 68071-5233; 0527-2933; 70518-1561; 70518-2676; 70518-3138; 71205-403; 71335-0464; 0615-8395; 72789-235; 0904-7127; 42708-167; 50090-3330; 50090-3354; 50090-5816; 51407-356; 51407-360; 51655-726; 55154-4949; 59651-484; 60760-715; 63629-2257; 68071-2781; 68788-8184; 0527-2930; 70518-0307; 70518-2555; 70518-3142; 70934-096; 70954-056; 71205-407; 71335-0623; 0054-4728; 0054-9817; 72162-1171; 75987-020; 10135-776; 60722-1002; 82298-103; 42291-771; 42708-114; 42708-166; 51655-349; 51655-760; 59651-486; 59746-173; 60219-1706; 60760-615; 63187-037; 67296-1083; 67296-1446; 67544-399; 0054-0017; 70518-3537; 70934-291; 0054-3722; 71205-362; 71335-0335; 71335-0508; 71335-2079; 71610-641; 72162-1172; 72189-246; 80425-0193; 38779-0154; 57582-003; 42708-045; 43063-866; 50090-6122; 51407-355; 51407-357; 51655-197; 51655-541; 51655-716; 53002-3250; 55700-203; 55700-209; 60687-134; 61919-326; 63187-020; 63629-1605; 63629-2259; 63629-2264; 63739-588; 64380-783; 67296-1203; 67296-1767; 67296-1886; 68071-2771; 70518-2314; 70518-2703; 70518-3401; 70518-3476; 70518-3539; 70518-3555; 70954-058; 71205-239; 71205-421; 71205-665; 71335-1915; 71335-2069; 71335-2160; 71335-9715; 72189-430; 0615-8391; 76420-069; 49452-6000; 10135-775; 42291-770; 42291-783; 50090-4785; 50090-5814; 50090-6376; 51407-358; 51407-359; 51655-208; 51655-939; 55154-3564; 58118-5442; 59651-485
UNII	VB0R961HZT
Synonyms	Prednisone \| Dehydrocortisone \| delta-Cortisone \| Rectodelt \| Prednison Hexal \| Sterapred \| Ultracorten \| Winpred \| Apo-Prednisone \| Cortan \| Cortancyl \| Panafcort \| Cutason \| Decortin \| Dacortin \| Decortisyl \| Deltasone \| Encortone \| Encorton \| Enkortolon \| Kortancyl \| Liquid Pred \| Meticorten \| Orasone \| Panasol \| Predni Tablinen \| Prednidib \| Predniment \| Prednison Acsis \| Acsis, Prednison \| Pronisone \| Sone \| Prednison Galen

Chemical Information

Molecular Formula	C21H26O5
CAS Registry Number	53-03-2
SMILES	CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C
Chemical Structure

ADRs Induced by Drug

*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..

ADR Term	ADReCS ID	ADR Frequency (FAERS)	ADR Severity Grade (FAERS)	ADR Severity Grade (CTCAE)
Cerebral artery thrombosis	24.01.04.008; 17.08.01.026	0.000009%		Not Available
Cervical spinal stenosis	17.10.02.006; 15.10.04.006	-	-	Not Available
Coeliac disease	07.17.01.008; 14.02.01.007; 10.04.04.012	0.000013%		Not Available
Colonic fistula	07.11.05.007	0.000009%
Concomitant disease aggravated	08.01.03.063	0.000027%		Not Available
Cryoglobulinaemia	10.04.04.013; 24.12.04.007	0.000009%		Not Available
Delusion of grandeur	19.10.01.004	0.000009%		Not Available
Dermatitis exfoliative generalised	23.03.07.002; 10.01.01.029	0.000031%		Not Available
Diffuse vasculitis	10.02.02.024; 24.12.04.009	0.000018%		Not Available
Enthesopathy	15.07.01.011	-	-	Not Available
Eosinophilic fasciitis	01.02.04.010; 15.06.01.013; 10.04.02.008	0.000018%		Not Available
Haemorrhagic cerebral infarction	24.07.04.026; 17.08.01.050	0.000013%		Not Available
Haemorrhagic infarction	24.04.02.008	0.000009%		Not Available
Hyperbilirubinaemia neonatal	09.01.01.014; 18.04.08.003; 17.13.01.009; 14.11.01.038	0.000009%		Not Available
Ileal stenosis	07.13.06.006	0.000022%
Intestinal fistula	07.11.05.012	0.000013%		Not Available
Jealous delusion	19.10.01.006	0.000009%		Not Available
Jejunal ulcer	07.04.06.012	0.000013%
Jugular vein thrombosis	24.01.02.007	0.000013%		Not Available
Large granular lymphocytosis	01.10.11.001; 16.01.11.001	0.000009%		Not Available
Lung adenocarcinoma	22.08.01.007; 16.19.01.002	0.000022%		Not Available
Lung adenocarcinoma stage IV	22.08.01.017; 16.19.01.007	0.000009%		Not Available
Lupus nephritis	20.05.02.003; 15.06.02.011; 10.04.03.011	0.000058%		Not Available
Lymphadenopathy mediastinal	01.09.01.025; 22.09.03.006	0.000018%		Not Available
Malignant neoplasm of spinal cord	17.20.04.003; 16.30.04.003	0.000009%		Not Available
Mesenteric vein thrombosis	24.01.08.004; 07.15.02.013	0.000009%		Not Available
Neonatal respiratory distress syndrome	22.11.02.010; 18.04.10.003	0.000013%		Not Available
Normal newborn	18.08.06.001	0.000029%		Not Available
Obstruction gastric	07.13.04.002	0.000013%
Oligodendroglioma	17.20.01.008; 16.30.01.008	0.000009%		Not Available

The 41th Page First Pre 41 42 43 44 45 Next Last Total 49 Pages