Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Silver
Drug ID BADD_D02023
Description Silver (Ag) is a chemical element that belongs in the family of transition metals in the periodic table. It has a high electrical conductivity, thermal conductivity, and reflectivity. Silver exists as a pure elemental form, alloy with other metals, and mineral. Having critical roles in various applications inducing chemical and industrial fields, silver compounds have also been used in the field of medicine for centuries due to their broad-spectrum biological actions. Silver nanoparticles especially have been widely used in industrial, household, and healthcare-related products due to their potent antimicrobial activity. [DB11080] and [DB05245] have been used as topical antibacterial agents for the treatment of skin infections, while [DB05245] has also been valued for topical burn treatment [A33141]. Silver and its compounds have been used in trials studying the management of dental caries since the 1800s, and they may be found in dental pastes as an active ingredients. However, some drawbacks of dental use of silver compounds include tooth discolouration and pulp irritation [A33141].
Indications and Usage Indicated for the treatment of acne for topical use or the management of dental caries for dental use.
Marketing Status approved; investigational
ATC Code D08AL30
DrugBank ID DB12965
KEGG ID Not Available
MeSH ID D012834
PubChem ID 23954
TTD Drug ID D08JCA
NDC Product Code 0220-0476; 81042-010; 64117-207; 63083-8148; 0220-0477; 55926-0025; 60319-2001; 62106-4871; 55926-0024; 0220-0478
UNII 3M4G523W1G
Synonyms Silver
Chemical Information
Molecular Formula Ag
CAS Registry Number 7440-22-4
SMILES [Ag]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bacterial disease carrier11.07.03.001--Not Available
Burning sensation17.02.06.001; 08.01.09.029--Not Available
Dermatitis23.03.04.002--Not Available
Erythema multiforme23.03.01.003; 10.01.03.015--
Leukopenia01.02.02.001--Not Available
Rash23.03.13.001--Not Available
Sepsis11.01.11.003--
Skin discolouration23.03.03.005--Not Available
Skin exfoliation23.03.07.003--Not Available
Skin necrosis23.03.03.011--Not Available
Tubulointerstitial nephritis20.05.02.002--Not Available
Muscle contracture15.03.05.024--Not Available
Partner stress26.04.01.002--Not Available
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