Adverse Drug Reaction Classification System

         

Pharmaceutical Information
Drug Name Trifluoperazine
Drug ID BADD_D02281
Description A phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Indications and Usage For the treatment of anxiety disorders, depressive symptoms secondary to anxiety and agitation.
Marketing Status approved; investigational
ATC Code N05AB06
DrugBank ID DB00831
KEGG ID D01448; D08636
MeSH ID D014268
PubChem ID 5566
TTD Drug ID D0R4OM
NDC Product Code Not Available
UNII 214IZI85K3
Synonyms Trifluoperazine | Trifluperazine | Trifluoroperazine | Eskazine | Flupazine | Terfluzine | Trifluoperazine Hydrochloride | Trifluoperazine HCL | Triftazin | Apo-Trifluoperazine | Apo Trifluoperazine | ApoTrifluoperazine | Stelazine
Chemical Information
Molecular Formula C21H24F3N3S
CAS Registry Number 117-89-5
SMILES CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Opisthotonus17.01.03.005--Not Available
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
Pancytopenia01.03.03.003--Not Available
Parkinsonism17.01.05.003--Not Available
Petit mal epilepsy17.12.04.001--Not Available
Photosensitivity reaction23.03.09.003--
Pregnancy test false positive13.10.05.003--Not Available
Priapism24.04.12.007; 21.03.01.005--Not Available
Protrusion tongue17.02.05.037; 07.14.02.002--Not Available
Pruritus23.03.12.001--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Retinal disorder06.08.03.005--Not Available
Retinal pigmentation06.09.03.008--Not Available
Salivary hypersecretion07.06.01.009--Not Available
Seizure17.12.03.001--
Skin disorder23.03.03.007--Not Available
Skin hyperpigmentation23.05.01.003--
Skin reaction23.03.03.013; 10.01.03.019--Not Available
Sleep disorder19.02.04.001--Not Available
Somnolence19.02.05.003; 17.02.04.006--
Speech disorder22.12.03.027; 19.19.02.002; 17.02.08.003--Not Available
Sudden death08.04.01.003; 02.03.04.013--
Systemic lupus erythematosus23.03.02.006; 15.06.02.003; 10.04.03.004--Not Available
Tachycardia02.03.02.007--Not Available
Tardive dyskinesia17.01.02.012--Not Available
Tetany15.05.03.013; 14.04.01.005; 05.04.02.003--Not Available
Throat tightness19.01.02.005; 22.12.03.031--Not Available
Thrombocytopenic purpura23.06.01.007; 01.08.01.003--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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