Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Hydrogen peroxide
Drug ID BADD_D02623
Description Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution. If heated to its boiling point, it may undergo potentially explosive thermal decomposition. Hydrogen peroxide is formed in the body of mammals during reduction of oxygen either directly in a two-electron transfer reaction [L2024]. As a natural product of metabolism, it readily undergoes decomposition by catalase in normal cells [L2024]. Due to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [A32369]. It is used in industrial and cosmetic applications as a bleaching agent. Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing agent in products containing dried eggs, dried egg whites, and dried egg yolks.
Indications and Usage Indicated to be used as a disinfectant and sterilizer.
Marketing Status approved; vet_approved
ATC Code A01AB02; D08AX01; D11AX25; S02AA06
DrugBank ID DB11091
KEGG ID D00008
MeSH ID D006861
PubChem ID 784
TTD Drug ID D03IDU
NDC Product Code 75908-017; 78495-152; 0924-0935; 30142-871; 41250-871; 47682-257; 47682-275; 53175-001; 55319-567; 55319-871; 63517-450; 79794-111; 11673-268; 50594-871; 50804-156; 51316-268; 53329-981; 55239-360; 57243-871; 67860-871; 68196-268; 69256-268; 76162-327; 78691-021; 83279-401; 21130-979; 0126-0083; 49035-267; 51532-5400; 53329-980; 53329-983; 56062-871; 63940-871; 67326-354; 70082-111; 53943-099; 53943-871; 55301-871; 55910-268; 55910-871; 59883-018; 63868-184; 68599-2305; 0869-0871; 17129-001; 37012-871; 39892-0700; 0363-0085; 66715-6846; 71927-013; 72288-871; 10565-001; 74556-002; 30400-250; 36800-214; 37205-871; 41190-871; 42681-6414; 47682-304; 47682-324; 47682-334; 52380-0013; 59779-871; 59883-017; 0363-0871; 63941-871; 68599-2301; 73408-257; 11673-327; 15127-871; 41250-268; 49348-179; 51048-040; 51628-4238; 55315-268; 60319-1001; 61010-5400; 61504-871; 68016-871; 11673-871; 21130-871; 39892-0710; 43128-001; 49035-871; 49580-0268; 49681-016; 50804-871; 53942-871; 61734-010; 0363-0267; 62011-0267; 63868-147; 0404-0001; 67091-407; 69103-5400; 70000-0022; 78495-162; 83123-0012; 74556-003; 11822-1462; 36800-871; 37808-871; 42961-016; 42961-216; 46994-871; 47682-259; 53329-086; 55319-268; 67326-353; 69842-008; 72476-942; 76176-111; 77210-0035; 49452-3600; 11822-0871; 11822-3155; 12745-202; 12745-205; 20276-300; 41163-871; 41250-750; 49035-268; 51316-078; 53462-075; 65055-501; 70000-0500; 0869-0462; 10202-001; 33992-0871; 46122-334; 51628-4231; 55239-450; 55316-871; 60319-5001
UNII BBX060AN9V
Synonyms Hydrogen Peroxide | Peroxide, Hydrogen | Hydrogen Peroxide (H2O2) | Hydroperoxide | Superoxol | Oxydol | Perhydrol
Chemical Information
Molecular Formula H2O2
CAS Registry Number 7722-84-1
SMILES OO
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Application site pain12.07.01.004; 08.02.01.004--Not Available
Blindness06.02.10.003; 17.17.01.003--Not Available
Blindness transient06.02.10.006; 17.17.01.004--Not Available
Contact lens intolerance06.01.01.003--Not Available
Corneal erosion06.06.03.003--Not Available
Dry eye06.08.02.001--
Dysphonia22.12.03.006; 19.19.03.002; 17.02.08.004--
Erythema23.03.06.001--Not Available
Eye disorder06.08.03.001--Not Available
Eye inflammation06.04.05.002--Not Available
Eye irritation06.04.05.003--Not Available
Eye pain06.08.03.002--
Eye swelling06.08.03.003--Not Available
Hypersensitivity10.01.03.003--
Keratitis06.04.02.002--
Lacrimation increased06.08.02.004--
Ocular hyperaemia06.04.05.004--Not Available
Photophobia17.17.02.006; 06.01.01.004--
Vision blurred17.17.01.010; 06.02.06.007--
Visual acuity reduced17.17.01.011; 06.02.10.012--
Visual impairment06.02.10.013--Not Available
Foreign body sensation in eyes06.01.01.006--Not Available
Eye complication associated with device06.08.03.020; 08.07.03.001--Not Available
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